1,2-Dihydrotanshinone (Synonyms: 1,2-Dihydrotanshinquinone)

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白、同位素标记物,专注于信号通路和疾病研究领域。
1,2-Dihydrotanshinone  (Synonyms: 1,2-Dihydrotanshinquinone)

1,2-Dihydrotanshinone (1,2-Dihydrotanshinquinone) 是一种松香烷二萜。1,2-Dihydrotanshinone 抑制 (CUG) n-RNA 和剪接因子 muscleblind-like 1 之间形成的致病复合物的形成。1,2-Dihydrotanshinone 可用于强直性肌营养不良 1 型的研究。

1,2-Dihydrotanshinone                                          (Synonyms: 1,2-Dihydrotanshinquinone)

1,2-Dihydrotanshinone Chemical Structure

CAS No. : 77769-21-2

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1,2-Dihydrotanshinone 相关产品

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生物活性

1,2-Dihydrotanshinone (1,2-Dihydrotanshinquinone) is an abietane diterpene. 1,2-Dihydrotanshinone inhibits the formation of the pathogenic complex formed between (CUG)n-RNA and the splicing-factor muscleblind-like 1 (MBNL1). 1,2-Dihydrotanshinone can be used for the research of myotonic dystrophy type 1[1][2].

体外研究
(In Vitro)

1,2-Dihydrotanshinone inhibits the formation of the pathogenic complex formed between (CUG)n-RNA and the splicing-factor muscleblind-like 1 (MBNL1) (≥50% inhibition at 100 µg/mL)[1].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.

1,2-Dihydrotanshinone 相关抗体:

分子量

278.30

Formula

C18H14O3

CAS 号

77769-21-2

结构分类
  • Terpenoids
  • Diterpenoids
初始来源
  • 植物
  • 豆科
  • 雨树
  • 植物
  • 唇形科
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
Data Sheet (534 KB) 产品使用指南 (1538 KB)

参考文献
  • [1]. Faleschini MT, et, al. Discovery of natural products potentially active against myotonic dystrophy type 1. Planta Med 2015; 81-YRW_03.

    [2]. Fronza M, et, al. In vitro cytotoxic activity of abietane diterpenes from Peltodon longipes as well as Salvia miltiorrhiza and Salvia sahendica. Bioorg Med Chem. 2011 Aug 15;19(16):4876-81.  [Content Brief]

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