分类目录归档：同位素标记物

Isotope-Labeled Compounds

N-Acetyl-D-mannosamine-18O(Synonyms: N-Acetylmannosamine-18O; ManNAc-18O)

发表于由

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白、同位素标记物，专注于信号通路和疾病研究领域。
N-Acetyl-D-mannosamine-18O (Synonyms: N-Acetylmannosamine-18O; ManNAc-18O)

N-Acetyl-D-mannosamine-18O 是 18O 标记的 N-Acetyl-D-mannosamine。 N-Acetyl-D-mannosamine (ManNAc) N-乙酰基-D-甘露糖胺是N-乙酰神经氨酸 (NeuAc) 的必需前体，细菌荚膜聚唾液酸(PA) 的特异性单体。 N-Acetyl-D-mannosamine (ManNAc) N-乙酰基-D-甘露糖胺分别通过 GNE 和 GlcNAc 2-差向异构酶 (肾素结合蛋白，RnBP) 代谢成 ManNAc-6-磷酸和 GlcN

N-Acetyl-D-mannosamine-18O(Synonyms: N-Acetylmannosamine-18O; ManNAc-18O)

N-Acetyl-D-mannosamine-18O Chemical Structure

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生物活性

N-Acetyl-D-mannosamine-18O is the 18O labeled N-Acetyl-D-mannosamine. N-Acetyl-D-mannosamine (ManNAc) is an essential precursor of N-acetylneuraminic acid (NeuAc), the specific monomer of bacterial capsular polysialic acid (PA)[1][2]

体外研究
(In Vitro)

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

223.21

Formula

C8H15NO518O
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
Data Sheet (494 KB) 产品使用指南 (1538 KB)

参考文献

  • [1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.

    [2]. Revilla-Nuin B, et al. Transport of N-acetyl-D-mannosamine and N-acetyl-D-glucosamine in Escherichia coli K1: effect on capsular polysialic acid production. FEBS Lett. 2002 Jan 30;511(1-3):97-101.;Hayakawa K, et al. Reactivation of hyperglycemia-induced h

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Glucosamine-15N hydrochloride(Synonyms: D-(+)-Glucosamine-15N hydrochloride; Chitosamine-15N hydrochloride)

发表于由

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白、同位素标记物，专注于信号通路和疾病研究领域。
Glucosamine-15N hydrochloride (Synonyms: D-(+)-Glucosamine-15N hydrochloride; Chitosamine-15N hydrochloride)

Glucosamine-15N hydrochloride 是 15N 标记的 Glucosamine hydrochloride。 Glucosamine hydrochloride (D-Glucosamine hydrochloride) 是一种氨基糖, 是糖基化蛋白和脂质生化合成的突出前体, 用作膳食补充剂。Glucosamine hydrochloride也是软骨基质和滑液中糖胺聚糖的天然成分，当外用时，对骨关节炎软骨和软骨细胞具有药理作用。

Glucosamine-15N hydrochloride(Synonyms: D-(+)-Glucosamine-15N hydrochloride; Chitosamine-15N hydrochloride)

Glucosamine-15N hydrochloride Chemical Structure

CAS No. : 42927-60-6

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生物活性

Glucosamine-15N hydrochloride is the 15N labeled Glucosamine hydrochloride. Glucosamine hydrochloride (D-Glucosamine hydrochloride) is an amino sugar and a prominent precursor in the biochemical synthesis of glycosylated proteins and lipids, is used as a

体外研究
(In Vitro)

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

216.63

Formula

C6H14Cl15NO5
CAS 号

42927-60-6
中文名称

盐酸氨基葡萄糖 15N；氨基葡萄糖盐酸盐 15N；D-氨基葡萄糖盐酸盐 15N
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
Data Sheet (487 KB) 产品使用指南 (1538 KB)

参考文献

  • [1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.

    [2]. Jamialahmadi K, et al. Protective effects of glucosamine hydrochloride against free radical-induced erythrocytes damage. Environ Toxicol Pharmacol. 2014 Jul;38(1):212-9.;Jo JR, et al. Short-term treatment with glucosamine hydrochloride specifically downre

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Xylose-d1-4(Synonyms: D-(+)-Xylose-d1-4; (+)-Xylose-d1-4; Wood sugar-d1-4)

发表于由

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白、同位素标记物，专注于信号通路和疾病研究领域。
Xylose-d1-4 (Synonyms: D-(+)-Xylose-d1-4; (+)-Xylose-d1-4; Wood sugar-d1-4)

Xylose-d1-4 是 Xylose 的氘代物。 D-(+)-木糖 (Xylose) 是一种天然化合物，经木糖异构酶催化形成木酮糖，这是木糖无氧乙醇发酵的关键步骤。

Xylose-d1-4(Synonyms: D-(+)-Xylose-d1-4; (+)-Xylose-d1-4; Wood sugar-d1-4)

Xylose-d1-4 Chemical Structure

CAS No. : 288846-91-3

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生物活性

Xylose-d1-4 is the deuterium labeled Xylose.

体外研究
(In Vitro)

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

151.14

Formula

C5H9DO5
CAS 号

288846-91-3
中文名称

木糖 d1-4；D-(+)-木糖 d1-4；五碳醛糖 d1-4
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
Data Sheet (489 KB) 产品使用指南 (1538 KB)

参考文献

  • [1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.

    [2]. Wang XX, et al. The implementation of high fermentative 2,3-butanediol production from xylose by simultaneous additions of yeast extract, Na2EDTA, and acetic acid. N Biotechnol. 2015 Aug 3.;Bingyin Peng, et al. Bacterial xylose isomerases from the mammal

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N-Acetylneuraminic acid-13C-1(Synonyms: NANA-13C-1; Lactaminic acid-13C-1)

发表于由

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白、同位素标记物，专注于信号通路和疾病研究领域。
N-Acetylneuraminic acid-13C-1 (Synonyms: NANA-13C-1; Lactaminic acid-13C-1)

N-Acetylneuraminic acid-13C-1 是 13C 标记的 N-Acetylneuraminic acid。 N-Acetylneuraminic酸是一个在细胞膜的糖蛋白和哺乳细胞神经节甘脂的糖脂上普遍存在的唾液酸单糖，在神经传递, 白细胞血管渗出，病毒或细菌感染起着生物作用。

N-Acetylneuraminic acid-13C-1(Synonyms: NANA-13C-1; Lactaminic acid-13C-1)

N-Acetylneuraminic acid-13C-1 Chemical Structure

CAS No. : 1032998-24-5

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生物活性

N-Acetylneuraminic acid-13C-1 is the 13C labeled N-Acetylneuraminic acid.

体外研究
(In Vitro)

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

310.26

Formula

C1013CH19NO9
CAS 号

1032998-24-5
中文名称

唾液酸 13C-1；N-乙酰神经氨酸 13C-1；醋纽拉酸 13C-1；N-乙酰涎酸 13C-1；氧-唾液酸 13C-1；N-乙酰-神经氨 (糖) 酸 13C-1
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
Data Sheet (490 KB) 产品使用指南 (1538 KB)

参考文献

  • [1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.

    [2]. Bondioli L et al. PLGA nanoparticles surface decorated with the sialic acid, N-acetylneuraminic acid. Biomaterials. 2010 Apr;31(12):3395-403.;Kiefel MJ, et al. Synthesis and biological evaluation of N-acetylneuraminic acid-based rotavirus inhibitors. J Me

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D-(+)-Trehalose-d2(Synonyms: D-Trehalose-d2; α,α-Trehalose-d2)

发表于由

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白、同位素标记物，专注于信号通路和疾病研究领域。
D-(+)-Trehalose-d2 (Synonyms: D-Trehalose-d2; α,α-Trehalose-d2)

D-(+)-Trehalose-d2 是 D-(+)-Trehalose 的氘代物。 D-(+)-Trehalose可从 Saccharomyces cerevisiae 中分离得到，常用作食品成分和药物赋形剂。

D-(+)-Trehalose-d2(Synonyms: D-Trehalose-d2; α,α-Trehalose-d2)

D-(+)-Trehalose-d2 Chemical Structure

CAS No. : 1334376-67-8

规格 是否有货
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生物活性

D-(+)-Trehalose-d2 is the deuterium labeled D-(+)-Trehalose. D-(+)-Trehalose, isolated from Saccharomyces cerevisiae, can be used as a food ingredient and pharmaceutical excipi[1][2].

体外研究
(In Vitro)

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

344.31

Formula

C12H20D2O11
CAS 号

1334376-67-8
中文名称

α,α-海藻糖 d2；α-D-吡喃葡萄糖基-α-D-吡喃葡萄糖苷 d2；D-海藻糖,无水 d2
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
Data Sheet (489 KB) 产品使用指南 (1538 KB)

参考文献

  • [1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.

    [2]. Megarry AJ, et al. Amorphous trehalose dihydrate by cryogenic milling. Carbohydr Res. 2011 Jun 1;346(8):1061-4.

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Adenosine-13C(Synonyms: Adenine riboside-13C; D-Adenosine-13C)

发表于由

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白、同位素标记物，专注于信号通路和疾病研究领域。
Adenosine-13C (Synonyms: Adenine riboside-13C; D-Adenosine-13C)

Adenosine-13C 是 13C 标记的 Adenosine。 Adenosine (Adenine riboside) 是一种普遍存在的内源性分泌物，是通过四种G蛋白偶联受体（A1、A2A、A2B 和 A3）的起作用。Adenosine 几乎影响细胞生理学的所有方面，包括神经元活动、血管功能、血小板聚集和血细胞调节。

Adenosine-13C(Synonyms: Adenine riboside-13C; D-Adenosine-13C)

Adenosine-13C Chemical Structure

CAS No. : 54447-57-3

规格 是否有货
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生物活性

Adenosine-13C is the 13C labeled Adenosine. Adenosine (Adenine riboside), a ubiquitous endogenous autacoid, acts through the enrollment of four G protein-coupled receptors: A1, A2A, A2B, and A3. Adenosine affects almost all aspects of cellular physiology,

体外研究
(In Vitro)

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

268.23

Formula

C913CH13N5O4
CAS 号

54447-57-3
中文名称

腺苷 13C
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
Data Sheet (503 KB) 产品使用指南 (1538 KB)

参考文献

  • [1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.

    [2]. Borea PA, Gessi S, Merighi S, Vincenzi F, Varani K. Pharmacology of Adenosine Receptors: The State of the Art. Physiol Rev. 2018;98(3):1591-1625.;Fredholm BB. Adenosine, an endogenous distress signal, modulates tissue damage and repair. Cell Death Differ.

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D-Ribose-13C,d(Synonyms: D-(-)-核糖 13C,d)

发表于由

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白、同位素标记物，专注于信号通路和疾病研究领域。
D-Ribose-13C,d (Synonyms: D-(-)-核糖 13C,d)

D-Ribose-13C,d 是 13C 标记的 D-Ribose 的氘代物。 D-Ribose 是一种能量增强剂，为 ATP 的糖部分，广泛用作慢性疲劳综合症和心肌能量代谢的代谢疗法补充剂。D-Ribose 在蛋白质糖化中具有活性，能够以 RAGE 依赖的方式诱导 NF-κB 炎症。

D-Ribose-13C,d(Synonyms: D-(-)-核糖 13C,d)

D-Ribose-13C,d Chemical Structure

规格 是否有货
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生物活性

D-Ribose-13C,d is the deuterium and 13C labeled D-Ribose. D-Ribose is an energy enhancer, and acts as a sugar moiety of ATP, and widely used as a metabolic therapy supplement for chronic fatigue syndrome or cardiac energy metabolism. D-Ribose is active in

体外研究
(In Vitro)

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

152.13

Formula

C413CH9DO5
中文名称

D-(-)-核糖 13C,d
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
Data Sheet (490 KB) 产品使用指南 (1538 KB)

参考文献

  • [1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.

    [2]. Hong J, et al. D-ribose induces nephropathy through RAGE-dependent NF-κB inflammation. Arch Pharm Res. 2018 Aug;41(8):838-847.

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Glucosamine-13C,15N hydrochloride(Synonyms: D-(+)-Glucosamine-13C,15N hydrochloride; Chitosamine-13C,15N hydrochloride)

发表于由

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白、同位素标记物，专注于信号通路和疾病研究领域。
Glucosamine-13C,15N hydrochloride (Synonyms: D-(+)-Glucosamine-13C,15N hydrochloride; Chitosamine-13C,15N hydrochloride)

Glucosamine-13C,15N hydrochloride 是 13C 和 15N 标记的 Glucosamine hydrochloride。 Glucosamine hydrochloride (D-Glucosamine hydrochloride) 是一种氨基糖, 是糖基化蛋白和脂质生化合成的突出前体, 用作膳食补充剂。Glucosamine hydrochloride也是软骨基质和滑液中糖胺聚糖的天然成分，当外用时，对骨关节炎软骨和软骨细胞具有药理作用。

Glucosamine-13C,15N hydrochloride(Synonyms: D-(+)-Glucosamine-13C,15N hydrochloride; Chitosamine-13C,15N hydrochloride)

Glucosamine-13C,15N hydrochloride Chemical Structure

CAS No. : 143553-09-7

规格 是否有货
100 mg   询价  
250 mg   询价  
500 mg   询价  

* Please select Quantity before adding items.

生物活性

Glucosamine-13C,15N hydrochloride is the 13C and 15N labeled Glucosamine hydrochloride. Glucosamine hydrochloride (D-Glucosamine hydrochloride) is an amino sugar and a prominent precursor in the biochemical synthesis of glycosylated proteins and lipids, i

体外研究
(In Vitro)

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

217.62

Formula

C513CH14Cl15NO5
CAS 号

143553-09-7
中文名称

盐酸氨基葡萄糖 13C,15N；氨基葡萄糖盐酸盐 13C,15N；D-氨基葡萄糖盐酸盐 13C,15N
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
Data Sheet (491 KB) 产品使用指南 (1538 KB)

参考文献

  • [1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.

    [2]. Jamialahmadi K, et al. Protective effects of glucosamine hydrochloride against free radical-induced erythrocytes damage. Environ Toxicol Pharmacol. 2014 Jul;38(1):212-9.;Jo JR, et al. Short-term treatment with glucosamine hydrochloride specifically downre

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Urea-13C(Synonyms: 尿素-13C)

发表于由

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白、同位素标记物，专注于信号通路和疾病研究领域。
Urea-13C (Synonyms: 尿素-13C)

13C-urea 是 13C 标记的尿素。13C-urea 呼气试验（13C-UBT）是诊断幽门螺杆菌感染的最佳方法之一。

Urea-13C(Synonyms: 尿素-13C)

Urea-13C Chemical Structure

CAS No. : 58069-82-2

规格 是否有货
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生物活性

13C-urea is the 13C labelled urea. The 13C-urea breath test (13C-UBT) is one of the best methods for the diagnosis of Helicobacter pylori infection[1].

分子量

61.05

Formula

13CH4N2O
CAS 号

58069-82-2
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
Data Sheet (455 KB) 产品使用指南 (1538 KB)

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D-(+)-Glucono-1,5-lactone-d2(Synonyms: Gluconic acid lactone-d2)

发表于由

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白、同位素标记物，专注于信号通路和疾病研究领域。
D-(+)-Glucono-1,5-lactone-d2 (Synonyms: Gluconic acid lactone-d2)

D-(+)-Glucono-1,5-lactone-d2 是 D-(+)-Glucono-1,5-lactone 的氘代物。 D-(+)-Glucono-1,5-lactone 是一种聚羟基酸，能够螯合金属离子，保湿，具有抗氧化活性。

D-(+)-Glucono-1,5-lactone-d2(Synonyms: Gluconic acid lactone-d2)

D-(+)-Glucono-1,5-lactone-d2 Chemical Structure

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生物活性

D-(+)-Glucono-1,5-lactone-d2 is the deuterium labeled D-(+)-Glucono-1,5-lactone. D-(+)-Glucono-1,5-lactone is a polyhydroxy (PHA) that is capable of metal chelating, moisturizing and antioxidant activ[1][2].

体外研究
(In Vitro)

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

180.15

Formula

C6H8D2O6
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
Data Sheet (493 KB) 产品使用指南 (1538 KB)

参考文献

  • [1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.

    [2]. Xu Y, et al. Aggregation and structural changes of silver carp actomyosin as affected by mild acidification with D-gluconic acid δ-lactone. Food Chem. 2012 Sep 15;134(2):1005-10.

所有产品仅用作科学研究或药证申报，我们不为任何个人用途提供产品和服务