Sodium 3-methyl-2-oxobutanoate (Synonyms: 3-甲基-2-氧代丁酸钠)

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白、同位素标记物,专注于信号通路和疾病研究领域。
Sodium 3-methyl-2-oxobutanoate  (Synonyms: 3-甲基-2-氧代丁酸钠) 纯度: 99.36%

Sodium 3-methyl-2-oxobutanoate 是大肠杆菌中泛酸的前体。

Sodium 3-methyl-2-oxobutanoate                                          (Synonyms: 3-甲基-2-氧代丁酸钠)

Sodium 3-methyl-2-oxobutanoate Chemical Structure

CAS No. : 3715-29-5

规格 价格 是否有货 数量
500 mg ¥500 In-stock
1 g ¥800 In-stock
5 g   询价  
10 g   询价  

* Please select Quantity before adding items.

Sodium 3-methyl-2-oxobutanoate 相关产品

相关化合物库:

  • Natural Product Library Plus
  • Bioactive Compound Library Plus
  • Metabolism/Protease Compound Library
  • Natural Product Library
  • Human Endogenous Metabolite Compound Library
  • Fragment Library
  • Gut Microbial Metabolite Library
  • Microbial Metabolite Library
  • Food-Sourced Compound Library
  • Human Metabolite Library
  • Animal-Sourced Natural Product Library
  • Multi-Target Compound Library

同靶点产品:

同靶点蛋白产品:

生物活性

Sodium 3-methyl-2-oxobutanoate is a precursor of pantothenic acid in Escherichia coli[1][2][3].

IC50 & Target

Microbial Metabolite

 

Human Endogenous Metabolite

 

体外研究
(In Vitro)

Sodium 3-methyl-2-oxobutanoate (alpha-Ketoisovaleric acid) is a precursor of pantothenic acid in Escherichia coli[1]. Sodium 3-methyl-2-oxobutanoate (alpha-Ketoisovaleric acid) enhances alpha-ketoisocaproic acid and alpha-keto-beta-methyl-n-valeric acid, but diminishes the corresponding amino acids, and causes an early decline of ornithine along with a late augmentation of plasma arginine[2].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.

Sodium 3-methyl-2-oxobutanoate 相关抗体:

体内研究
(In Vivo)

Sodium 3-methyl-2-oxobutanoate (alpha-Ketoisovaleric acid) induces convulsions through GABAergic and glutamatergic mechanisms in rats[3].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

138.10

Formula

C5H7NaO3

CAS 号

3715-29-5

性状

固体

颜色

White to light brown

结构分类
  • Ketones, Aldehydes, Acids
初始来源
  • 内源性代谢物
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

4°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

溶解性数据
In Vitro: 

H2O 中的溶解度 : ≥ 100 mg/mL (724.11 mM)

* “≥” means soluble, but saturation unknown.

配制储备液
浓度 溶剂体积 质量 1 mg 5 mg 10 mg
1 mM 7.2411 mL 36.2056 mL 72.4113 mL
5 mM 1.4482 mL 7.2411 mL 14.4823 mL
10 mM 0.7241 mL 3.6206 mL 7.2411 mL

查看完整储备液配制表

* 请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效
储备液的保存方式和期限:-80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)。-80°C储存时,请在6个月内使用,-20°C储存时,请在1个月内使用。

* 备注:如您选择水作为储备液,请稀释至工作液后,再用 0.22 μm 的滤膜过滤除菌后使用。

  • 摩尔计算器

  • 稀释计算器

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量

=

浓度

×

体积

×

分子量 *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start)

C1

×

体积 (start)

V1

=

浓度 (final)

C2

×

体积 (final)

V2

In Vivo:

以下溶解方案,请直接配置工作液。建议现用现配,在短期内尽快用完。 以下溶剂前显示的百分比是指该溶剂在您配制终溶液中的体积占比; 如在配制过程中出现沉淀、析出现象,可以通过加热和/或超声的方式助溶。

  • 方案 一

    请依序添加每种溶剂: PBS

    Solubility: 100 mg/mL (724.11 mM); 澄清溶液; 超声助溶

扫码获得
动物溶解方案

动物溶解方案计算器
请输入动物实验的基本信息:

给药剂量

mg/kg

动物的平均体重

g

每只动物的给药体积

μL

动物数量

由于实验过程有损耗,建议您多配一只动物的量

计算结果
工作液所需浓度 : mg/mL

该产品水溶性佳,请具体参考实测 水 / PBS / Saline 中的溶解度数据。
免费服务热线:021-50837765
E-mail:sales@jinpanbio.com
技术支持电话:021-50837765
技术支持邮箱:sales@jinpanbio.com

纯度 & 产品资料

纯度: 99.36%

Data Sheet (608 KB) SDS (0 KB)

COA (192 KB) RP-HPLC (190 KB) LCMS (88 KB)

产品使用指南 (1538 KB)

参考文献
  • [1]. MAAS WK, et al. alpha-Ketoisovaleric acid, a precursor of pantothenic acid in Escherichia coli. J Bacteriol. 1953 Apr;65(4):388-93.  [Content Brief]

    [2]. Schauder P, et al. Oral administration of alpha-ketoisovaleric acid or valine in humans: blood kinetics and biochemical effects. J Lab Clin Med. 1984 Apr;103(4):597-605.  [Content Brief]

    [3]. Coitinho AS, et al. Pharmacological evidence that alpha-ketoisovaleric acid induces convulsions through GABAergic and glutamatergic mechanisms in rats. Brain Res. 2001 Mar 9;894(1):68-73.  [Content Brief]

所有产品仅用作科学研究或药证申报,我们不为任何个人用途提供产品和服务