标签归档：dithiocarboxyglucamine

N-methyl-N-dithiocarboxyglucamine (Synonyms: MDCG)

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N-methyl-N-dithiocarboxyglucamine  (Synonyms: MDCG)

N-methyl-N-dithiocarboxyglucamine (MDCG) 能够动员和促进金属硫蛋白结合的 109Cd 的排泄。N-methyl-N-dithiocarboxyglucamine 对急性和慢性镉中毒均有效。

N-methyl-N-dithiocarboxyglucamine (Synonyms: MDCG)

N-methyl-N-dithiocarboxyglucamine Chemical Structure

CAS No. : 94161-07-6

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N-methyl-N-dithiocarboxyglucamine 的其他形式现货产品:

N-methyl-N-dithiocarboxyglucamine sodium

N-methyl-N-dithiocarboxyglucamine 相关产品

•同靶点产品:

•同靶点蛋白产品:

生物活性

N-methyl-N-dithiocarboxyglucamine (MDCG) mobilizes and promotes excretion of metallothione-bound 109Cd. N-methyl-N-dithiocarboxyglucamine shows effects on acute and chronic Cd intoxication[1].

体内研究
(In Vivo)

N-methyl-N-dithiocarboxyglucamine (684-2736 mg/kg；腹腔注射，每日注射 3 次) 3 天内有效促进粪便镉排泄[1]。
N-methyl-N-dithiocarboxyglucamine (2736 mg/kg；腹腔注射，每周注射 3 次) 降低肾脏和肝脏的镉水平[1]。

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Mice with CdCl2 injection[1]
Dosage: 684, 1368 and 2736 mg/kg
Administration: Intraperitoneal injection; 684, 1368 and 2736 mg/kg, three daily injection
Result: Dose-dependently increased fecal Cd excretion and caused a fecal Cd excretion of almost 30% of the administered Cd over a 3-day period at a dose of 2736 mg/kg.

分子量

271.35

Formula

C8H17NO5S2
CAS 号

94161-07-6
结构分类
  • Others
初始来源
  • 内源性代谢物
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
Data Sheet (525 KB) 产品使用指南 (1538 KB)

参考文献

  • [1]. Gale GR, et al. Effects of sodium N-methyl-N-dithiocarboxyglucamine on cadmium distribution and excretion. Life Sci. 1984 Dec 17;35(25):2571-8.  [Content Brief]

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