标签归档：蟾蜍

Hellebrigenin (Synonyms: 蟾蜍它里定)

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Hellebrigenin  (Synonyms: 蟾蜍它里定) 纯度: ≥99.0%

Hellebrigenin，属于心脏活性类固醇的丁二烯内酯之一，从中药中分离出来。Hellebrigenin 诱导 DNA 损伤和细胞周期 G2/M 阻滞。 Hellebrigenin 触发线粒体介导的细胞凋亡。

Hellebrigenin (Synonyms: 蟾蜍它里定)

Hellebrigenin Chemical Structure

CAS No. : 465-90-7

规格 价格 是否有货 数量
1 mg ￥1250 In-stock
5 mg ￥3200 In-stock
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Hellebrigenin 相关产品

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生物活性

Hellebrigenin, one of bufadienolides belonging to cardioactive steroids, is isolated from traditional Chinese medicine Venenum Bufonis. Hellebrigenin induces DNA damage and cell cycle G2/M arrest. Hellebrigenin triggers mitochondria-mediated apoptosis.

分子量

416.51

Formula

C24H32O6
CAS 号

465-90-7
性状

固体

颜色

White to off-white

中文名称

蟾蜍它里定
结构分类
  • Steroids
初始来源
  • 动物

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运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

4°C, sealed storage, away from moisture and light

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

纯度 & 产品资料

纯度: ≥99.0%

Data Sheet (531 KB) SDS (251 KB)

COA (270 KB)

产品使用指南 (1538 KB)

参考文献

  • [1]. Deng LJ, et al. Hellebrigenin induces cell cycle arrest and apoptosis in human hepatocellular carcinoma HepG2 cells through inhibition of Akt. Chem Biol Interact. 2014 Aug 5;219:184-94.  [Content Brief]

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