标签归档：刺五加

Ciwujianoside C3 (Synonyms: 刺五加苷 C3)

发表于由

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白、同位素标记物，专注于信号通路和疾病研究领域。
Ciwujianoside C3  (Synonyms: 刺五加苷 C3) 纯度: ≥98.0%

Ciwujianoside C3 是一种具有口服活性并可以穿透血脑屏障的化合物，分离于刺五加的叶子。 Ciwujianoside C3 具有抗炎作用，并可以增强小鼠个体的识别记忆力。

Ciwujianoside C3 (Synonyms: 刺五加苷 C3)

Ciwujianoside C3 Chemical Structure

CAS No. : 114906-74-0

规格 价格 是否有货 数量
1 mg ￥3123 In-stock
5 mg ￥8200 In-stock
10 mg   询价  
50 mg   询价  

* Please select Quantity before adding items.

Ciwujianoside C3 相关产品

•相关化合物库:

  • Natural Product Library Plus
  • Bioactive Compound Library Plus

•同靶点产品:

•同靶点蛋白产品:

生物活性

Ciwujianoside C3, an orally active and brain penetrated compound, is isolated the leaves of Acanthopanax henryi Harms. Ciwujianoside C3 has anti-inflammatory effect and can reinforces object recognition memory[1][2].

体外研究
(In Vitro)

Ciwujianoside C3 相关抗体:

Cell Viability Assay[1]

Cell Line: RAW 264.7 cells
Concentration: 10 µM, 20 µM and 40 µM
Incubation Time: 24 hours
Result: Has no effect on cell cytotoxicity and inhibits NO production

Western Blot Analysis[1]

Cell Line: RAW 264.7 cells
Concentration: 10 µM, 20 µM and 40 µM
Incubation Time: 24 hours
Result: Decreases p-ERK and p-JNK expression.

RT-PCR[1]

Cell Line: RAW 264.7 cells
Concentration: 10 µM, 20 µM and 40 µM
Incubation Time: 24 hours
Result: Decreased COX-2 and iNOS mRNA expression in a dose-dependent manner.

体内研究
(In Vivo)
Animal Model: Mice[1]
Dosage: 0.5 mg/kg
Administration: Oral administration; 0.5 mg/kg/day; 17 days
Result: Reinforced object recognition memory.

分子量

1059.24

Formula

C53H86O21
CAS 号

114906-74-0
性状

固体

颜色

White to off-white

中文名称

刺五加苷 C3
结构分类
  • Others
初始来源
  • 植物
  • 五加科
  • 糙叶五加
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
纯度 & 产品资料

纯度: ≥98.0%

Data Sheet (530 KB) SDS (251 KB)

COA (202 KB)

产品使用指南 (1538 KB)

参考文献

  • [1]. Kang DH, et al. Anti-inflammatory effects of Ciwujianoside C3, extracted from the leaves of Acanthopanax henryi (Oliv.) Harms, on LPS-stimulated RAW 264.7 cells. Mol Med Rep. 2016 Oct;14(4):3749-58.  [Content Brief]

    [2]. Yamauchi Y, et al. Memory Enhancement by Oral Administration of Extract of Eleutherococcus senticosus Leaves and Active Compounds Transferred in the Brain.Nutrients. 2019 May 22;11(5).  [Content Brief]

所有产品仅用作科学研究或药证申报，我们不为任何个人用途提供产品和服务