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Pristinamycin (Synonyms: 棱镜霉素; Pristinamycine) 纯度: 99.63%
Pristinamycin 是一种具有口服活性的链霉素样的抗生素，产生于 Streptomyces pristinaespiralis，Pristinamycin 由两种化学上不相关的成分组成：Pristinamycin I (PI) 和 Pristinamycin II (PII)。Pristinamycin 对多种抗生素耐药病原菌，特别是革兰氏阳性菌，包括耐甲氧西林金黄色葡萄球菌 (MRSA)、万古霉素耐药金黄色葡萄球菌 (VRSA) 和粪肠球菌 (VREF) 具有高度的活性。
Pristinamycin Chemical Structure
CAS No. : 270076-60-3
| 规格 | 价格 | 是否有货 | 数量 |
|---|---|---|---|
| 5 mg | ￥2500 | In-stock | |
| 10 mg | ￥4000 | In-stock | |
| 25 mg | ￥8500 | In-stock | |
| 50 mg | 询价 | ||
| 100 mg | 询价 |
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| 生物活性 |
Pristinamycin, produced by Streptomyces pristinaespiralis, is an orally active streptogramin-like antibiotic consisting of two chemically unrelated components: Pristinamycin I (PI) and Pristinamycin II (PII). Pristinamycin is highly active against many antibiotic-resistant pathogens, particularly Gram-positive bacteria, including Methicillin-resistant Staphylococcus aureus (MRSA), Vancomycin-resistant S. aureus (VRSA) and Enterococcus faecium (VREF)[1]. |
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| 体外研究 (In Vitro) |
In-vitro studies show pristinamycin to inhibit Staphylococci and Streptococci, including Erythromycin highly-resistant organisms, at a concentration of less than or equal to 0.78 mg/l[2]. Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only. |
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| 体内研究 (In Vivo) |
To study Pristinamycin activity in vivo, mice infected IP with C. psittaci. Mortality in the control group was 70%. Three groups of mice received 25 mg/kg, 50 mg/kg and 100 mg/kg Pristinamycin respectively. The antibiotic was active in the 100 mg/kg dosage which is the therapeutic dosage[3]. Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only. |
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| Clinical Trial |
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| 分子量 |
1392.55 |
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| Formula |
C73H89N11O17 |
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| CAS 号 |
270076-60-3 |
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| 性状 |
固体 |
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| 颜色 |
Light yellow to yellow |
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| 中文名称 |
棱镜霉素 |
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| 结构分类 |
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| 初始来源 |
streptogramin |
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| 运输条件 |
Room temperature in continental US; may vary elsewhere. |
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| 储存方式 |
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| 溶解性数据 |
In Vitro:
DMSO 中的溶解度 : 100 mg/mL (71.81 mM; 超声助溶; 吸湿的 DMSO 对产品的溶解度有显著影响，请使用新开封的 DMSO) 配制储备液
查看完整储备液配制表
* 请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)
Concentration (start) × Volume (start) = Concentration (final) × Volume (final) This equation is commonly abbreviated as: C1V1 = C2V2
动物溶解方案计算器
请输入动物实验的基本信息：
给药剂量 mg/kg 动物的平均体重 g 每只动物的给药体积 μL 动物数量 只 由于实验过程有损耗，建议您多配一只动物的量
计算结果
工作液所需浓度 : mg/mL
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| 纯度 & 产品资料 |
纯度: 99.63%
Data Sheet (539 KB) SDS (251 KB)
COA (180 KB) LCMS (109 KB) 产品使用指南 (1538 KB) |
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| 参考文献 |
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