上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白、同位素标记物,专注于信号通路和疾病研究领域。
Olopatadine
Olopatadine 是一种具有口服活性和选择性的组胺 1 (H1) 受体拮抗剂,也是肥大细胞稳定剂。Olopatadine 可以防止人结膜肥大细胞释放免疫刺激的促炎介质。Olopatadine 可用于过敏性结膜炎的研究。
Olopatadine Chemical Structure
CAS No. : 113806-05-6
规格 | 价格 | 是否有货 | |
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5 mg | ¥1440 | 询问价格 & 货期 |
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Olopatadine 的其他形式现货产品:
生物活性 |
Olopatadine is an orally active and selective histamine 1 (H1) receptor antagonist and a mast cell stabilizer. Olopatadine prevents immunologically stimulated pro-inflammatory mediator release from human conjunctival mast cells. Olopatadine can be used for researching allergic conjunctivitis[1][2]. |
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IC50 & Target[1] |
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体外研究 (In Vitro) |
Olopatadine inhibits anti-IgE antibody-mediated release of TNF-α from human conjunctival mast cells, and significantly decreases the mast cell supernatant-mediated upregulation of ICAM (intercellular adhesion molecule)-1 on human conjunctival epithelial cells in vitro[2]. Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only. |
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Clinical Trial |
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分子量 |
337.41 |
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Formula |
C21H23NO3 |
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CAS 号 |
113806-05-6 |
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结构分类 |
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初始来源 |
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运输条件 |
Room temperature in continental US; may vary elsewhere. |
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储存方式 |
Please store the product under the recommended conditions in the Certificate of Analysis. |
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纯度 & 产品资料 |
Data Sheet (534 KB) 产品使用指南 (1538 KB)
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参考文献 |
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