Atropine-d5(Synonyms: Tropine tropate-d5; DL-Hyoscyamine-d5)

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Atropine-d5 (Synonyms: Tropine tropate-d5; DL-Hyoscyamine-d5)

Atropine-d5 (Tropine tropate-d5) 是 Atropine (sulfate monohydrate) 的氘代物。Atropine (Tropine tropate) sulfate monohydrate 是广谱的，竞争性的毒蕈碱乙酰胆碱受体 (mAChR) 拮抗剂，具有抗近视作用。

Atropine-d5(Synonyms: Tropine tropate-d5; DL-Hyoscyamine-d5)

Atropine-d5 Chemical Structure

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生物活性

Atropine-d5 (Tropine tropate-d5) is the deuterium labeled Atropine (sulfate monohydrate). Atropine (Tropine tropate) sulfate monohydrate is a broad-spectrum and competitive muscarinic acetylcholine receptor (mAChR) antagonist with anti-myopia effect[1].

体外研究
(In Vitro)

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

294.40

Formula

C17H18D5NO3
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.

    [2]. McBrien NA, et al. How does atropine exert its anti-myopia effects? Ophthalmic Physiol Opt. 2013 May;33(3):373-8.

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