(Rac)-Salvianic acid A (Synonyms: (Rac)-丹参素; (Rac)-Danshensu; (Rac)-Tanshinol)

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白、同位素标记物,专注于信号通路和疾病研究领域。
(Rac)-Salvianic acid A  (Synonyms: (Rac)-丹参素; (Rac)-Danshensu; (Rac)-Tanshinol)

(Rac)-Salvianic acid A 是 Salvianic acid A (HY-N1913) 的外消旋体。Salvianic acid A 是一种具有口服活性的酚类化合物,可诱导 Nrf2/HO-1 激活并抑制 NF-κB 通路。Danshensu 具有抗氧化、抗凋亡、抗肺部炎症等作用,具有用于 COVID-19、心脑血管等疾病研究的潜力。

(Rac)-Salvianic acid A                                          (Synonyms: (Rac)-丹参素; (Rac)-Danshensu;  (Rac)-Tanshinol)

(Rac)-Salvianic acid A Chemical Structure

CAS No. : 23028-17-3

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(Rac)-Salvianic acid A 相关产品

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生物活性

(Rac)-Salvianic acid A is the racemate of Salvianic acid A (HY-N1913). Salvianic acid A, an orally active phenolic compound, can induce Nrf2/HO-1 activation and inhibition of NF-κB pathway. Danshensu has anti-oxidation, anti-apoptosis, anti-lung inflammatory and has the potential for COVID-19, cardiovascular and cerebrovascular diseases research[1][2][3].

分子量

198.17

Formula

C9H10O5

CAS 号

23028-17-3

性状

固体

颜色

Light yellow to yellow

中文名称

(Rac)-丹参素

结构分类
  • Phenols
  • Polyphenols
  • Ketones, Aldehydes, Acids
初始来源
  • 植物
  • 豆科
  • 雨树
  • 植物
  • 唇形科
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
Data Sheet (528 KB) 产品使用指南 (1538 KB)

参考文献
  • [1]. Wei Wang, et al. Danshensu alleviates pseudo-typed SARS-CoV-2 induced mouse acute lung inflammation. Acta Pharmacol Sin. 2022 Apr;43(4):771-780.  [Content Brief]

    [2]. V Bharath Kumar, et al. Sodium Danshensu Inhibits Oral Cancer Cell Migration and Invasion by Modulating p38 Signaling Pathway. Front Endocrinol (Lausanne). 2020 Sep 30:11:568436.  [Content Brief]

    [3]. Chen Yu, et al. Danshensu attenuates cisplatin-induced nephrotoxicity through activation of Nrf2 pathway and inhibition of NF-κB. Biomed Pharmacother. 2021 Oct:142:111995.  [Content Brief]

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