标签归档：cbz

Z-D-Phg-OH(Synonyms: D-Cbz phenylglycine)

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上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白、同位素标记物，专注于信号通路和疾病研究领域。
Z-D-Phg-OH (Synonyms: D-Cbz phenylglycine)

Z-D-Phg-OH (D-Cbz phenylglycine) 是一种 N 端封闭氨基酸 (N-blocked amino acids)，对 tBuCQN 和 tBuCQD 的 Kd 分别为 390 μM 和 323 μM。

Z-D-Phg-OH(Synonyms: D-Cbz phenylglycine)

Z-D-Phg-OH Chemical Structure

CAS No. : 17609-52-8

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生物活性

Z-D-Phg-OH (D-Cbz phenylglycine) is a N-blocked amino acids with Kd values of 390 μM and 323 μM for tBuCQN and tBuCQD, respectively[1].

IC50 & Target

Kd: 390 μM (tBuCQN), 323 μM (tBuCQD)[1]
分子量

285.29

Formula

C16H15NO4
CAS 号

17609-52-8
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. Frycák P, et al. High throughput multiplexed method for evaluation of enantioselective performance of chiral selectors by HPLC-ESI-MS and dynamic titration: cinchona alkaloid carbamates discriminating N-blocked amino acids. Chirality. 2009 Nov;21(10):929-36.

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N-Cbz-O-Bzl-L-Glu-S-Bzl-L-Cys-Gly-OBzl-13C2,15N

发表于由

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白、同位素标记物，专注于信号通路和疾病研究领域。
N-Cbz-O-Bzl-L-Glu-S-Bzl-L-Cys-Gly-OBzl-13C2,15N 

N-Cbz-O-Bzl-L-Glu-S-Bzl-L-Cys-Gly-OBzl-13C2,15N 是一种 15N 标记和 13C 标记的 N-Cbz-O-Bzl-L-Glu-S-Bzl-L-Cys-Gly-OBzl 化合物。

N-Cbz-O-Bzl-L-Glu-S-Bzl-L-Cys-Gly-OBzl-13C2,15N

N-Cbz-O-Bzl-L-Glu-S-Bzl-L-Cys-Gly-OBzl-13C2,15N Chemical Structure

规格 是否有货
100 mg   询价  
250 mg   询价  
500 mg   询价  

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生物活性

N-Cbz-O-Bzl-L-Glu-S-Bzl-L-Cys-Gly-OBzl-13C2,15N is a 15N-labeled and 13C-labled labeled N-Cbz-O-Bzl-L-Glu-S-Bzl-L-Cys-Gly-OBzl[1].

体外研究
(In Vitro)

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[70].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

714.80

Formula

C3713C2H41N215NO8S
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-223.

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Carbamazepine-d10(Synonyms: CBZ-d10; NSC 169864-d10)

发表于由

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白、同位素标记物，专注于信号通路和疾病研究领域。
Carbamazepine-d10 (Synonyms: CBZ-d10; NSC 169864-d10)

Carbamazepine-D10 (CBZ-d10) 是 Carbamazepine 的氘代物。Carbamazepine (CBZ) 是压敏钠离子通道阻断剂，IC50 为 131 μM。

Carbamazepine-d10(Synonyms: CBZ-d10; NSC 169864-d10)

Carbamazepine-d10 Chemical Structure

CAS No. : 132183-78-9

规格 是否有货
2.5 mg Check price and availability
1 mg Check price and availability

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生物活性

Carbamazepine-D10 (CBZ-d10) is the deuterium labeled Carbamazepine. Carbamazepine (CBZ), a sodium channel blocker, is an anticonvulsant agent[1][2].

体外研究
(In Vitro)

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

246.33

Formula

C15H2D10N2O
CAS 号

132183-78-9
中文名称

卡马西平 D10
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.

    [2]. Willow, M. and W.A. Catterall, Inhibition of binding of [3H]batrachotoxinin A 20-alpha-benzoate to sodium channels by the anticonvulsant drugs diphenylhydantoin and carbamazepine. Mol Pharmacol, 1982. 22(3): p. 627-35.

    [3]. Okada, M., et al., Biphasic effects of carbamazepine on the dopaminergic system in rat striatum and hippocampus. Epilepsy Res, 1997. 28(2): p. 143-53.

所有产品仅用作科学研究或药证申报，我们不为任何个人用途提供产品和服务

Carbamazepine-d2(Synonyms: CBZ-d2; NSC 169864-d2)

发表于由

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白、同位素标记物，专注于信号通路和疾病研究领域。
Carbamazepine-d2 (Synonyms: CBZ-d2; NSC 169864-d2)

Carbamazepine-d2 (CBZ-d2) 是 Carbamazepine 的氘代物。Carbamazepine是压敏钠离子通道阻断剂，IC50为 131 μM。

Carbamazepine-d2(Synonyms: CBZ-d2; NSC 169864-d2)

Carbamazepine-d2 Chemical Structure

CAS No. : 1189902-21-3

规格 是否有货
1 mg Check price and availability
10 mg Check price and availability

* Please select Quantity before adding items.

生物活性

Carbamazepine-d2 (CBZ-d2) is the deuterium labeled Carbamazepine. Carbamazepine, a sodium channel blocker, is an anticonvulsant drug.

体外研究
(In Vitro)

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

238.28

Formula

C15H10D2N2O
CAS 号

1189902-21-3
中文名称

卡马西平 D2
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.

    [2]. Willow, M. and W.A. Catterall, Inhibition of binding of [3H]batrachotoxinin A 20-alpha-benzoate to sodium channels by the anticonvulsant drugs diphenylhydantoin and carbamazepine. Mol Pharmacol, 1982. 22(3): p. 627-35.

    [3]. Okada, M., et al., Biphasic effects of carbamazepine on the dopaminergic system in rat striatum and hippocampus. Epilepsy Res, 1997. 28(2): p. 143-53.

所有产品仅用作科学研究或药证申报，我们不为任何个人用途提供产品和服务