AL-3138 (11-Deoxy-16-fluoro PGF2α) is a prostaglandin F2 alpha (PGF2alpha) analogue that antagonises FP prostaglandin receptor-mediated inositol phosphate production^[1].

AL-3138 对 A7r5 细胞和 3T3 细胞的作用EC₅₀ 值分别为 72.2 nM 和 20.5 nM。此外，AL-3138 在 A7r5 细胞中对氟苯尼考的作用被确定为 K_i = 296 nM 和 K_b = 182 nM^[1]。

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.

356.47

C₂₀H₃₃FO₄

64603-03-8

• Others

• 内源性代谢物

Room temperature in continental US; may vary elsewhere.

Please store the product under the recommended conditions in the Certificate of Analysis.

• [1]. Sharif NA, et al. AL-3138 antagonizes FP prostanoid receptor-mediated inositol phosphates generation: comparison with some purported FP antagonists. J Pharm Pharmacol. 2000 Dec;52(12):1529-39.   [Content Brief]