标签归档：酒石酸

L-Tartaric acid diammonium (Synonyms: L-酒石酸铵; 酒石酸二铵盐; L-(+)-Tartaric acid diammonium)

发表于由

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L-Tartaric acid diammonium  (Synonyms: L-酒石酸铵; 酒石酸二铵盐; L-(+)-Tartaric acid diammonium)

L-Tartaric acid diammonium (L-(+)-Tartaric acid) 是具有口服活性的可以从葡萄中分离得到的弱有机酸。L-Tartaric acid diammonium 具有血管舒张和抗高血压的作用。L-Tartaric acid diammonium 可用于一系列食品和饮料的调味剂和抗氧化剂。L-Tartaric acid diammonium 可以用于激光倍频和光限幅应用中。

L-Tartaric acid diammonium (Synonyms: L-酒石酸铵; 酒石酸二铵盐; L-(+)-Tartaric acid diammonium)

L-Tartaric acid diammonium Chemical Structure

CAS No. : 3164-29-2

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L-Tartaric acid diammonium 的其他形式现货产品:

L-Tartaric acid

L-Tartaric acid diammonium 相关产品

•同靶点产品:

•同靶点蛋白产品:

生物活性

L-Tartaric acid diammonium (L-(+) -tartaric acid) is an orally active weak organic acid that can be isolated from grapes. L-Tartaric acid diammonium has vasodilatory and antihypertensive effects. L-Tartaric acid diammonium can be used as flavorings and antioxidants in a range of foods and beverages. L-Tartaric acid diammonium can be used in laser frequency doubling and optical limiting applications[1][2][3][4].

IC50 & Target

Microbial Metabolite

 

Human Endogenous Metabolite

 

体外研究
(In Vitro)

L-Tartaric acid (1.66-6.64 mM) 显著降低 NEP 和 KCL 诱导的主动脉环血管收缩，EC50 分别为 4.119 mM 和 4.00 mM[3]。

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.

L-Tartaric acid diammonium 相关抗体:
体内研究
(In Vivo)

L-Tartaric acid (80-240 mg/kg; 口服给药; 单剂量) 在 L-NAME (60 mg/kg) 诱导的高血压小鼠中可以 降低小鼠的血压[3]。

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Hypertensive Wistar rat model[3]
Dosage: 80 mg/kg, 240 mg/kg
Administration: Oral gavage (p.o.); Single dose. After L-NAME treatment (60.mg/kg; p.o.)
Result: Reduced systolic blood pressure (SABP) and mild blood pressure (mid-BP) in rats at a dose of 240mg/kg, but had no effect on mean artery pressure, diastolic blood pressure, pulse pressure level, and heart rate.

分子量

184.15

Formula

C4H12N2O6
CAS 号

3164-29-2
中文名称

L-酒石酸铵； 酒石酸二铵盐
结构分类
  • Ketones, Aldehydes, Acids
初始来源
  • 内源性代谢物
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
Data Sheet (535 KB) 产品使用指南 (1538 KB)

参考文献

  • [1]. Sasikala V, et al. Growth, molecular structure, NBO analysis and vibrational spectral analysis of l-tartaric acid single crystal. Spectrochim Acta A Mol Biomol Spectrosc. 2014 Apr 5;123:127-41.  [Content Brief]

    [2]. DeBolt S, et al. L-tartaric acid synthesis from vitamin C in higher plants. Proc Natl Acad Sci U S A. 2006 Apr 4;103(14):5608-13.  [Content Brief]

    [3]. Amssayef A, et al. L-Tartaric Acid Exhibits Antihypertensive and Vasorelaxant Effects: The Possible Role of eNOS/NO/cGMP Pathways. Cardiovasc Hematol Agents Med Chem. 2023;21(3):202-212.  [Content Brief]

    [4]. EFSA Panel on Food Additives and Flavourings (FAF); Younes M, et al. Re-evaluation of l(+)-tartaric acid (E 334), sodium tartrates (E 335), potassium tartrates (E 336), potassium sodium tartrate (E 337) and calcium tartrate (E 354) as food additives. EFSA J. 2020 Mar 11;18(3):e06030.  [Content Brief]

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