上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白、同位素标记物，专注于信号通路和疾病研究领域。
Stiripentol-d9 (Synonyms: 斯利潘托 d9)
Stiripentol-d9 (BCX2600-d9) 是 Stiripentol 的氘代物。Stiripentol (STP) 是一种抗惊厥剂，其可以抑制由 CYP3A4 (非竞争性) 和 CYP2C19 (竞争性地) 介导的 CLB 向 N-desmethylclobazam (NCLB) 的 N-去甲基化，其 Ki 值分别为 1.59±0.07 和 0.516±0.065 μM，IC50 值分别为 1.58 和 3.29 μM。
Stiripentol-d9 Chemical Structure
CAS No. : 1185239-64-8
| 规格 | 是否有货 | ||
|---|---|---|---|
| 1 mg | Check price and availability | ||
| 10 mg | Check price and availability | ||
* Please select Quantity before adding items.
| 生物活性 |
Stiripentol-d9 (BCX2600-d9) is the deuterium labeled Stiripentol. Stiripentol (STP) is an anticonvulsant agent, which can inhibit N-demethylation of CLB to NCLB mediatated by CYP3A4 (noncompetitively) and CYP2C19 (competitively) with Ki of 1.59±0.07 and 0.516±0.065 μM and IC50 of 1.58 and 3.29 μM, respectively[1][2]. |
|---|---|
| 体外研究 (In Vitro) |
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1]. Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only. |
| 分子量 |
243.35 |
| Formula |
C14H9D9O3 |
| CAS 号 |
1185239-64-8 |
| 中文名称 |
斯利潘托 d9 |
| 运输条件 |
Room temperature in continental US; may vary elsewhere. |
| 储存方式 |
Please store the product under the recommended conditions in the Certificate of Analysis. |
| 参考文献 |
|
所有产品仅用作科学研究或药证申报，我们不为任何个人用途提供产品和服务