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Sphinganine 1-phosphate (Synonyms: D-erythro-Dihydrosphingosine 1-phosphate) 纯度: ≥99.0%
Sphinganine 1-phosphate (D-erythro-Dihydrosphingosine 1-phosphate) 是一种极性鞘脂代谢物,可调节细胞迁移、细胞分化等众多生理过程。
Sphinganine 1-phosphate Chemical Structure
CAS No. : 19794-97-9
规格 | 价格 | 是否有货 | 数量 |
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1 mg | ¥3500 | In-stock | |
5 mg | 询价 | ||
10 mg | 询价 |
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生物活性 |
Sphinganine 1-phosphate (D-erythro-Dihydrosphingosine 1-phosphate) is a polar sphingolipid metabolite that regulates cell migration, differentiation, survival and complex physiological processes[1]. |
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IC50 & Target |
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体外研究 (In Vitro) |
Sphinganine 1-phosphate (S1P) is a potent signaling molecule involved in cell stress responses, cancer, angiogenesis and lymphocyte trafficking. Sphinganine 1-phosphate functions primarily by activating a subgroup of the endothelial differentiation gene (EDG) family of G-protein coupled cell surface receptors. Sphinganine 1-phosphate has opposite effects in the regulation of cell metabolism. Sphinganine 1-phosphate regulates skeletal muscle differentiation and regeneration[1]. Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only. Cell Viability Assay[2]
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体内研究 (In Vivo) |
Sphinganine 1-phosphate can enhance wound healing in diabetic mice[1]. Sphinganine 1-phosphate provides renal and hepatic protection after liver ischemia and reperfusion (IR) injury in mice through selective activation of S1P1 receptors and pertussis toxin-sensitive G-proteins with subsequent activation of ERK and Akt. Sphinganine 1-phosphate (administered 0.1 mg/kg i.v. immediately before reperfusion and 0.2 mg/kg s.c. 2 h after reperfusion) protects against hepatic and renal injury after liver IR[2]. Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.
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分子量 |
381.49 |
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Formula |
C18H40NO5P |
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CAS 号 |
19794-97-9 |
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性状 |
固体 |
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颜色 |
White to off-white |
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结构分类 |
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初始来源 |
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运输条件 |
Room temperature in continental US; may vary elsewhere. |
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储存方式 |
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溶解性数据 |
In Vitro:
0.3 M NaOH 中的溶解度 : 4 mg/mL (10.49 mM; 超声加热助溶) 配制储备液
查看完整储备液配制表
* 请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效。
Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)
Concentration (start) × Volume (start) = Concentration (final) × Volume (final) This equation is commonly abbreviated as: C1V1 = C2V2
动物溶解方案计算器
请输入动物实验的基本信息:
给药剂量 mg/kg 动物的平均体重 g 每只动物的给药体积 μL 动物数量 只 由于实验过程有损耗,建议您多配一只动物的量
计算结果
工作液所需浓度 : mg/mL
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纯度 & 产品资料 |
纯度: ≥99.0%
Data Sheet (596 KB) SDS (0 KB)
COA (184 KB) 产品使用指南 (1538 KB) |
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参考文献 |
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