(S)-(+)-Modafinic acid-d5

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(S)-(+)-Modafinic acid-d5 

(S)-(+)-Modafinic acid-d5 是 (S)-(+)-Modafinic acid 氘代物。(S)-(+)-Modafinic acid是Modafinil(HY-10521A)的主要代谢产物。

(S)-(+)-Modafinic acid-d5

(S)-(+)-Modafinic acid-d5 Chemical Structure

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生物活性

(S)-(+)-Modafinic acid-d5 is deuterium labeled (S)-(+)-Modafinic acid.

体外研究
(In Vitro)

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

279.37

Formula

C15H9D5O3S

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • [1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.

    [2]. Ke-hua Wu, et al. Population pharmacokinetics of modafinil acid and estimation of the metabolic conversion of modafinil into modafinil acid in 5 major ethnic groups of China. Acta Pharmacologica Sinica (2012) 33: 1401–1408.

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