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Chlorpyrifos-d10
Chlorpyrifos-d10 是 Chlorpyrifos 的氘代物。Chlorpyrifos 是一种有机磷酸酯杀虫剂，被归类为亚硫磷。Chlorpyrifos 的氧代谢产物是 AChE 的抑制剂，可影响昆虫，人类和其他动物的神经功能。Chlorpyrifos oxon (CPO) 代谢物可被血浆酶对氧磷酶 1 (PON1) 水解，PON1 的过表达减轻了与 CPO 暴露相关的神经毒性。
Chlorpyrifos-d10 Chemical Structure
CAS No. : 285138-81-0
| 规格 | 价格 | 是否有货 | 数量 |
|---|---|---|---|
| 1 mg | ￥1600 | In-stock | |
| 5 mg | ￥3200 | In-stock | |
| 10 mg | ￥5600 | In-stock | |
| 50 mg | 询价 | ||
| 100 mg | 询价 |
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| 生物活性 |
Chlorpyrifos-d10 is the deuterium labeled Chlorpyrifos. Chlorpyrifos is an organophosphate insecticide that is classified as a phosphorothionate. The oxon metabolite of Chlorpyrifos is an inhibitor of acetylcholinesterase (AChE), affecting neurological function in insects, humans, and other animals. The Chlorpyrifos oxon (CPO) metabolite is hydrolyzed by the plasma enzyme paraoxonase 1 (PON1), and susceptibility to neurotoxicity associated with CPO exposure is mitigated by PON1 overexpression. |
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| 体外研究 (In Vitro) |
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1]. Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only. |
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| 分子量 |
360.65 |
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| Formula |
C9HD10Cl3NO3PS |
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| CAS 号 |
285138-81-0 |
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| 运输条件 |
Room temperature in continental US; may vary elsewhere. |
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| 储存方式 |
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| 参考文献 |
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