Methicillin-d6 sodium salt(Synonyms: 甲氧西林钠 d6 (钠盐))

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Methicillin-d6 sodium salt (Synonyms: 甲氧西林钠 d6 (钠盐))

Methicillin-d6 sodium 是 Methicillin sodium salt 的氘代物。Methicillin sodium salt (Meticillin sodium) 是β-内酰胺抗生素,其通过抑制参与肽聚糖合成的青霉素结合蛋白起作用。

Methicillin-d6 sodium salt(Synonyms: 甲氧西林钠 d6 (钠盐))

Methicillin-d6 sodium salt Chemical Structure

CAS No. : 1356847-96-5

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生物活性

Methicillin-d6 sodium salt is the deuterium labeled Methicillin sodium salt. Methicillin sodium salt is a β-lactam antibiotic which acts by inhibiting penicillin-binding proteins that are involved in the synthesis of peptidoglycan.

体外研究
(In Vitro)

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

408.43

Formula

C17H14D6N2NaO6S

CAS 号

1356847-96-5

中文名称

甲氧西林钠 d6 (钠盐)

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • [1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.

    [2]. Yang X, et al.Exosome-encapsulated antibiotic against intracellular infections of methicillin-resistant Staphylococcus aureus. Int J Nanomedicine. 2018 Nov 29;13:8095-8104.

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