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Girinimbine (Synonyms: Girinimbin)
Girinimbine (Girinimbin) 是一种咔唑类生物碱,具有多种生物学作用。Girinimbine 可诱导细胞凋亡 (apoptosis),具有抗锥虫、抗血小板活性、抗菌活性、抗炎、抗氧化和抗肿瘤活性。
Girinimbine Chemical Structure
CAS No. : 23095-44-5
规格 | 价格 | 是否有货 | 数量 |
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1 mg | ¥4000 | In-stock | |
5 mg | ¥10000 | In-stock | |
10 mg | 询价 | ||
50 mg | 询价 |
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Girinimbine 相关产品
•相关化合物库:
- Natural Product Library Plus
- Bioactive Compound Library Plus
生物活性 |
Girinimbine (Girinimbin) is a carbazole alkaloid with a variety of biological effects. Girinimbine can induce apoptosis, and has antitrypanosomal, antiplatelet activity, antibacterial activity, anti-inflammatory, antioxidant and antitumor activities[1][2][3]. |
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体外研究 (In Vitro) |
Girinimbine (1-400 µM; 24-72 h) decreases the viability of HepG2 cells in 24, 48 and 72 h with IC50 values of 61 µM, 56 µM, and 40 µM respectively. Girinimbine (10-100 µM; 24-48 h) increase of LDH leakage in both concentration- and time-dependent manner in HepG2 cells[1]. Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only. Cell Viability Assay[1]
Apoptosis Analysis[1]
Cell Cycle Analysis[1]
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体内研究 (In Vivo) |
Girinimbine (10-100 mg/kg; orally gavage; once) pretreatment helps limit total leukocyte migration, and reduced pro-inflammatory cytokine (IL-1β, TNF-α) levels in the peritoneal fluid[2]. Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.
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分子量 |
263.33 |
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Formula |
C18H17NO |
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CAS 号 |
23095-44-5 |
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性状 |
固体 |
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颜色 |
Off-white to light yellow |
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中文名称 |
吉九里香碱 |
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结构分类 |
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初始来源 |
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运输条件 |
Room temperature in continental US; may vary elsewhere. |
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储存方式 |
4°C, sealed storage, away from moisture and light *In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light) |
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纯度 & 产品资料 |
Data Sheet (537 KB) 产品使用指南 (1538 KB)
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参考文献 |
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