Gluten Exorphin B5

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Gluten Exorphin B5 

Gluten Exorphin B5 是一种来源于面筋粉的一种内源性阿片样肽，作用于阿片受体 (opioid receptor)能够提高大鼠餐后血浆胰岛素水平。

Gluten Exorphin B5

Gluten Exorphin B5 Chemical Structure

CAS No. : 68382-18-3

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Gluten Exorphin B5 相关产品

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生物活性

Gluten Exorphin B5 is an exogenous opioid peptides derived from wheat gluten, acts on opioid receptor, increases postprandial plasma insulin level in rats[1].

IC50 & Target

Opioid receptor[1]
分子量

594.66

Formula

C30H38N6O7
CAS 号

68382-18-3
Sequence

Tyr-Gly-Gly-Trp-Leu
Sequence Shortening

YGGWL
结构分类
  • Phenols
  • Monophenols
  • Others
初始来源
  • 植物
  • 禾亚科
  • 小麦
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
Solvent & Solubility
In Vitro: 

H2O

Peptide Solubility and Storage Guidelines:

1.  Calculate the length of the peptide.

2.  Calculate the overall charge of the entire peptide according to the following table:

  Contents Assign value
Acidic amino acid Asp (D), Glu (E), and the C-terminal -COOH. -1
Basic amino acid Arg (R), Lys (K), His (H), and the N-terminal -NH2 +1
Neutral amino acid Gly (G), Ala (A), Leu (L), Ile (I), Val (V), Cys (C), Met (M), Thr (T), Ser (S), Phe (F), Tyr (Y), Trp (W), Pro (P), Asn (N), Gln (Q) 0

3.  Recommended solution:

Overall charge of peptide Details
Negative (<0) 1.  Try to dissolve the peptide in water first.
2.  If water fails, add NH4OH (<50 μL).
3.  If the peptide still does not dissolve, add DMSO (50-100 μL) to solubilize the peptide.
Positive (>0) 1.  Try to dissolve the peptide in water first.
2.  If water fails, try dissolving the peptide in a 10%-30% acetic acid solution.
3.  If the peptide still does not dissolve, try dissolving the peptide in a small amount of DMSO.
Zero (=0) 1.  Try to dissolve the peptide in organic solvent (acetonitrile, methanol, etc.) first.
2.  For very hydrophobic peptides, try dissolving the peptide in a small amount of DMSO, and then dilute the solution with water to the desired concentration.
纯度 & 产品资料
Data Sheet (525 KB) 产品使用指南 (1538 KB)

参考文献

  • [1]. Fukudome S, et al. Effect of gluten exorphins A5 and B5 on the postprandial plasma insulin level in conscious rats. Life Sci. 1995;57(7):729-34.  [Content Brief]

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