9,10-Dihydroxystearic acid (Synonyms: 9,10-二羟硬脂酸；9,10-二羟基十八酸)

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9,10-Dihydroxystearic acid  (Synonyms: 9,10-二羟硬脂酸；9,10-二羟基十八酸)

9,10-Dihydroxystearic acid 是油酸的氧化产物，可以改善 KKAy 小鼠的葡萄糖耐量和胰岛素敏感性。

9,10-Dihydroxystearic acid (Synonyms: 9,10-二羟硬脂酸；9,10-二羟基十八酸)

9,10-Dihydroxystearic acid Chemical Structure

CAS No. : 120-87-6

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9,10-Dihydroxystearic acid 相关产品

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生物活性

9,10-Dihydroxystearic acid is an oxidation product of oleic acid. 9,10-Dihydroxystearic acid can improve glucose tolerance and insulin sensitivity in KKAy mice[1].

体外研究
(In Vitro)

5-20 μmol/L 9,10-Dihydroxystearic acid (DHSA) does not activate PPAR-γ in CV-1 cells but 50-100 μmol/L DHSA activates PPAR-γ in a dose-dependent way. 9,10-Dihydroxystearic acid does not activate PPAR-α in CV-1 cells[1].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.

9,10-Dihydroxystearic acid 相关抗体:
体内研究
(In Vivo)

9,10-Dihydroxystearic acid (DHSA; fed with high fat diet containing 4% DHSA; for 5-6 weeks) treatment improves glucose tolerance and insulin sensitivity in KKAy mice[1].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

316.48

Formula

C18H36O4
CAS 号

120-87-6
中文名称

9,10-二羟硬脂酸；9,10-二羟基十八酸
结构分类
  • Ketones, Aldehydes, Acids
初始来源
  • 植物
  • 大戟科
  • 蓖麻
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
Data Sheet (521 KB) 产品使用指南 (1538 KB)

参考文献

  • [1]. Xiaoming Yu, et al. Effects of 9,10-dihydroxysteatic acid on glucose metabolism in KKAy mice. Wei Sheng Yan Jiu. 2010 Jul;39(4):423-5.  [Content Brief]

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