标签归档：hydroxyestrone

4-Hydroxyestrone (Synonyms: 4-羟基雌酮; 4-OHE1)

发表于由

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4-Hydroxyestrone  (Synonyms: 4-羟基雌酮; 4-OHE1) 纯度: ≥99.0%

4-Hydroxyestrone (4-OHE1) 是一种雌酮代谢物，对氧化神经毒性具有很强的神经保护作用。4-Hydroxyestrone 增加了由 SIRT1 介导的 p53 去乙酰化导致的 p53 的细胞质易位。4-Hydroxyestrone 几乎没有雌激素活性

4-Hydroxyestrone (Synonyms: 4-羟基雌酮; 4-OHE1)

4-Hydroxyestrone Chemical Structure

CAS No. : 3131-23-5

规格 价格 是否有货 数量
1 mg ￥2200 In-stock
5 mg ￥5500 In-stock
10 mg ￥8800 In-stock
50 mg   询价  
100 mg   询价  

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4-Hydroxyestrone 相关产品

•相关化合物库:

  • Natural Product Library Plus
  • Bioactive Compound Library Plus
  • Metabolism/Protease Compound Library
  • Natural Product Library
  • Glycoside Compound Library
  • Neuroprotective Compound Library
  • Food-Sourced Compound Library
  • Human Metabolite Library
  • Cysteine Targeted Covalent Library
  • Animal-Sourced Natural Product Library

•同靶点产品:

•同靶点蛋白产品:

生物活性

4-Hydroxyestrone (4-OHE1), an estrone metabolite, has strong neuroprotective effect against oxidative neurotoxicity. 4-Hydroxyestrone increases cytoplasmic translocation of p53 resulting from SIRT1-mediated deacetylation of p53. 4-Hydroxyestrone has little estrogenic activity[1].

分子量

286.37

Formula

C18H22O3
CAS 号

3131-23-5
性状

固体

颜色

Light yellow to yellow

中文名称

4-羟基雌酮
结构分类
  • Others
初始来源
  • 动物
  • 内源性代谢物
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式
Powder -20°C 3 years
In solvent -80°C 6 months
-20°C 1 month
纯度 & 产品资料

纯度: ≥99.0%

Data Sheet (528 KB) SDS (393 KB)

COA (197 KB)

产品使用指南 (1538 KB)

参考文献

  • [1]. Hye Joung Choi, et al. 4-Hydroxyestrone, an Endogenous Estrogen Metabolite, Can Strongly Protect Neuronal Cells Against Oxidative Damage. Sci Rep. 2020 Apr 29;10(1):7283.  [Content Brief]

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