Ribitol-2-13C(Synonyms: Adonitol-2-13C; Adonite-2-13C)

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Ribitol-2-13C (Synonyms: Adonitol-2-13C; Adonite-2-13C)

Ribitol-2-13C 是 13C 标记的 Ribitol。 Ribitol 是一种戊糖醇,可通过核糖还原形成。在酿酒酵母 (Saccharomyces cerevisiae) 中增强 D-葡萄糖转向戊糖磷酸途径,可用于生产 D-核糖和核糖醇。

Ribitol-2-13C(Synonyms: Adonitol-2-13C;  Adonite-2-13C)

Ribitol-2-13C Chemical Structure

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生物活性

Ribitol-2-13C is the 13C labeled Ribitol. Ribitol is a crystalline pentose alcohol formed by the reduction of ribose. Enhancing the flux of D-glucose to the pentose phosphate pathway in Saccharomyces cerevisiae for the production of D-ribose and ribitol

体外研究
(In Vitro)

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

153.14

Formula

C413CH12O5

中文名称

核糖醇 2-13C;核醣醇 2-13C;侧金盏花醇 2-13C;戊五醇 2-13C;侧金盏花醇 2-13C;阿东糖醇 2-13C

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • [1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.

    [2]. Praissman JL, et al. The functional O-mannose glycan on α-dystroglycan contains a phospho-Ribitol primed for matriglycan addition. Elife. 2016 Apr 29;5. pii: e14473.;Toivari MH, et al. Enhancing the flux of D-glucose to the pentose phosphate pathway in Sa

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