D(+)-Galactosamine-13C,15N hydrochloride(Synonyms: D-Galactosamine-13C,15N hydrochloride)

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D(+)-Galactosamine-13C,15N hydrochloride (Synonyms: D-Galactosamine-13C,15N hydrochloride)

D(+)-Galactosamine-13C,15N hydrochloride 是 13C 和 15N 标记的 D(+)-Galactosamine hydrochloride。 D(+)-Galactosamine (D-Galactosamine) hydrochloride是一种已确定的实验毒素，主要通过产生自由基和UTP核苷酸的消耗引起肝损伤。D(+)-Galactosamine hydrochloride 中毒也会导致肾功能不全，所以，肾功能衰竭通常和终末期肝损伤有关。脂多糖/D(+)-Gal

D(+)-Galactosamine-13C,15N hydrochloride(Synonyms: D-Galactosamine-13C,15N hydrochloride)

D(+)-Galactosamine-13C,15N hydrochloride Chemical Structure

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生物活性

D(+)-Galactosamine-13C,15N hydrochloride is the 13C and 15N labeled D(+)-Galactosamine hydrochloride. D(+)-Galactosamine (D-Galactosamine) hydrochloride, which is an established experimental toxin, primarily causes liver injury by the generation of free r

体外研究
(In Vitro)

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

217.62

Formula

C513CH14Cl15NO5
中文名称

D-氨基半乳糖盐酸盐 13C,15N
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.

    [2]. Ayhanci A, et al. Protective effects of ellagic acid in D-galactosamine-induced kidney damage in rats. Cytotechnology. 2016;68(5):1763-1770. ;Okumura A, et al. Alleviation of lipopolysaccharide/d-galactosamine-induced liver injury in leukocyte cell-derive

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