N-Acetylneuraminic acid-d3(Synonyms: NANA-d3; Lactaminic acid-d3)

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N-Acetylneuraminic acid-d3 (Synonyms: NANA-d3; Lactaminic acid-d3)

N-Acetylneuraminic acid-d3 是 N-Acetylneuraminic acid 的氘代物。 N-Acetylneuraminic酸是一个在细胞膜的糖蛋白和哺乳细胞神经节甘脂的糖脂上普遍存在的唾液酸单糖，在神经传递, 白细胞血管渗出，病毒或细菌感染起着生物作用。

N-Acetylneuraminic acid-d3(Synonyms: NANA-d3; Lactaminic acid-d3)

N-Acetylneuraminic acid-d3 Chemical Structure

CAS No. : 86582-98-1

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生物活性

N-Acetylneuraminic acid-d3 is the deuterium labeled N-Acetylneuraminic acid.

体外研究
(In Vitro)

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

312.29

Formula

C11H16D3NO9
CAS 号

86582-98-1
中文名称

唾液酸 d3；N-乙酰神经氨酸 d3；醋纽拉酸 d3；N-乙酰涎酸 d3；氧-唾液酸 d3；N-乙酰-神经氨 (糖) 酸 d3
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.

    [2]. Bondioli L et al. PLGA nanoparticles surface decorated with the sialic acid, N-acetylneuraminic acid. Biomaterials. 2010 Apr;31(12):3395-403.;Kiefel MJ, et al. Synthesis and biological evaluation of N-acetylneuraminic acid-based rotavirus inhibitors. J Me

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