Tricaprilin-d15(Synonyms: Trioctanoin-d15; Glyceryl trioctanoate-d15)

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Tricaprilin-d15 (Synonyms: Trioctanoin-d15; Glyceryl trioctanoate-d15)

Tricaprilin-d15 是 Tricaprilin 氘代物。Tricaprilin (Trioctanoin) 用于轻度到中度阿尔茨海默病患者的研究，具有抗惊厥和植物代谢产物的作用。

Tricaprilin-d15(Synonyms: Trioctanoin-d15; Glyceryl trioctanoate-d15)

Tricaprilin-d15 Chemical Structure

CAS No. : 352431-24-4

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生物活性

Tricaprilin-d15 is the deuterium labeled Tricaprilin. Tricaprilin (Trioctanoin) is used in study for patients with mild to moderate Alzheimer’s disease and has a role as an anticonvulsant and a plant metabolite[1][2].

体外研究
(In Vitro)

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

515.96

Formula

C27H5D45O6
CAS 号

352431-24-4
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.

    [2]. Tricaprylin

    [3]. Kwok MK, et al. Re-thinking Alzheimer’s disease therapeutic targets using gene-based tests. EBioMedicine. 2018 Nov;37:461-470.

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