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Naloxegol-d5 oxalate
Naloxegol-d5 (oxalate) 是 Naloxegol (oxalate) 氘代物。Naloxegol oxalate (NKTR-118 oxalate; AZ-13337019 oxalate) 是一种 μ- 阿片受体拮抗剂。Naloxegol oxalate 能抑制阿片结合胃肠道 μ- 阿片受体,能有效减轻阿片类药物引起的便秘。
Naloxegol-d5 oxalate Chemical Structure
规格 | 是否有货 | ||
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100 mg | 询价 | ||
250 mg | 询价 | ||
500 mg | 询价 |
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生物活性 |
Naloxegol-d5 (oxalate) is deuterium labeled Naloxegol (oxalate). Naloxegol oxalate (NKTR-118 oxalate; AZ-13337019 oxalate) is a μ-opioid-receptor antagonist. Naloxegol oxalate inhibits opioid binding in μ-opioid receptors in the gastrointestinal tract and effective for alleviating opioid-induced constipation[1][2]. |
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体外研究 (In Vitro) |
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1]. Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only. |
分子量 |
746.85 |
Formula |
C36H50D5NO15 |
运输条件 |
Room temperature in continental US; may vary elsewhere. |
储存方式 |
Please store the product under the recommended conditions in the Certificate of Analysis. |
参考文献 |
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