Lidanserin-d6(Synonyms: ZK-33839-d6)

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Lidanserin-d6 (Synonyms: ZK-33839-d6)

Lidanserin-d6 (ZK-33839-d6) 是 Lidanserin 的氘代物。Lidanserin (ZK-33839) 是一种 5-HT_2A 和 α₁ 肾上腺素能受体 (adrenergic receptor) 拮抗剂。

Lidanserin-d6 Chemical Structure

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生物活性	Lidanserin-d6 (ZK-33839-d6) is the deuterium labeled Lidanserin. Lidanserin (ZK-33839) acts as a 5-HT_2A and α₁-adrenergic receptor antagonist.
体外研究 (In Vitro)	Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs^[1]. Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.
分子量	460.57
Formula	C₂₆H₂₅D₆FN₂O₄
中文名称	利丹色林 d6
运输条件	Room temperature in continental US; may vary elsewhere.
储存方式	Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献	[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [2]. Boichenko I, et al. Chemical Ligand Space of Cereblon. ACS Omega. 2018 Sep 14;3(9):11163-11171.

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