Calcitriol-13C3(Synonyms: 1,25-Dihydroxyvitamin D3-13C3)

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Calcitriol-13C3 (Synonyms: 1,25-Dihydroxyvitamin D3-13C3)

Calcitriol-13C3 (1,25-Dihydroxyvitamin D3-13C3) 是一种 13C 标记的 Calcitriol。Calcitriol 是活性最大的 vitamin D 代谢物，也是 vitamin D 受体 (VDR) 的激动剂。

Calcitriol-13C3 Chemical Structure

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生物活性	Calcitriol-13C3 (1,25-Dihydroxyvitamin D3-13C3) is the 13C-labeled Calcitriol. Calcitriol is the most active metabolite of vitamin D and also a vitamin D receptor (VDR) agonist.
体外研究 (In Vitro)	Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs^[1]. Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.
分子量	413.57
Formula	C₂₄¹³C₃H₃₈O₃
中文名称	骨化三醇 13C3
运输条件	Room temperature in continental US; may vary elsewhere.
储存方式	Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献	[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [2]. Zhang XF, et al. A-887826 is a structurally novel, potent and voltage-dependent Na(v)1.8 sodium channel blocker that attenuates neuropathic tactile allodynia in rats. Neuropharmacology. 2010 Sep;59(3):201-7.

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