Sotalol-d6 hydrochloride(Synonyms: MJ 1999-d6 hydrochloride)

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上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白、同位素标记物，专注于信号通路和疾病研究领域。
Sotalol-d6 hydrochloride (Synonyms: MJ 1999-d6 hydrochloride)

Sotalol-d6 (MJ 1999-d6) hydrochloride 是 Sotalol hydrochloride 的氘代物。Sotalol hydrochloride 是一种口服有效，非选择性 β-肾上腺素受体阻断剂。Sotalol hydrochloride 具有抗心律失常作用，可用于小儿心律失常的研究。Sotalol hydrochloride 阻断 β 受体和钾 KCNH2 通道。

Sotalol-d6 hydrochloride(Synonyms: MJ 1999-d6 hydrochloride)

Sotalol-d6 hydrochloride Chemical Structure

CAS No. : 1246820-85-8

规格 价格 是否有货
5 mg ￥6300 询问价格 & 货期
10 mg ￥10000 询问价格 & 货期

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生物活性

Sotalol-d6 (MJ 1999-d6) hydrochloride is a deuterium labeled Sotalol hydrochloride. Sotalol hydrochloride is an orally active, non-selective competitive β-adrenergic receptor blocker. Sotalol hydrochloride is a potent antiarrhythmic agent that can be used for the research of pediatric arrhythmias. Sotalol hydrochloride blocks β-receptors, and potassium KCNH2 channels[1][2].

分子量

314.86

Formula

C12H15D6ClN2O3S
CAS 号

1246820-85-8
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. Marta Reyes-Corral, et al. Differential Free Intracellular Calcium Release by Class II Antiarrhythmics in Cancer Cell Lines. J Pharmacol Exp Ther. 2019 Apr;369(1):152-162.

    [2]. Xiaomei Li, et al. Pediatric Dosing of Intravenous Sotalol Based on Body Surface Area in Patients with Arrhythmia. Pediatr Cardiol. 2017 Oct;38(7):1450-1455.

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