Hydroxy ipronidazole-d3

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Hydroxy ipronidazole-d3 

Hydroxy ipronidazole-d3 是 Hydroxy ipronidazole 的氘代物。Hydroxy ipronidazole (Ipronidazole-OH) 是硝基咪唑类抗生素的代谢物，如异丙咪唑 (IPZ)。Hydroxy ipronidazole (Ipronidazole-OH) 可能具有与亲本化合物相似的诱变潜力。

Hydroxy ipronidazole-d3

Hydroxy ipronidazole-d3 Chemical Structure

CAS No. : 1156508-86-9

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生物活性

Hydroxy ipronidazole-d3 is the deuterium labeled Hydroxy ipronidazole. Hydroxy ipronidazole (Ipronidazole-OH) is a metabolite of nitroimidazole antibiotics, such as ipronidazole (IPZ). Hydroxy ipronidazole may has similar mutagenic potential as the parent compound[1].

体外研究
(In Vitro)

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

188.20

Formula

C7H8D3N3O3
CAS 号

1156508-86-9
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.

    [2]. Kamila Mitrowska, et al. Transfer of nitroimidazoles from contaminated beeswax to honey. Food Addit Contam Part A Chem Anal Control Expo Risk Assess.2017 Apr;34(4):573-581.

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