Debutyldronedarone D6 hydrochloride(Synonyms: SR35021 D6 hydrochloride)

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Debutyldronedarone D6 hydrochloride (Synonyms: SR35021 D6 hydrochloride)

Debutyldronedarone D6 hydrochloride (SR35021 D6 hydrochloride) 是 Debutyldronedarone 的氘代物。Debutyldronedarone 是 Dronedarone (HY-A0016) 在人体中的主要循环活性代谢物 (metabolite)。Debutyldronedarone 的效力是Dronedarone 的1/10 到 1/3。

Debutyldronedarone D6 hydrochloride(Synonyms: SR35021 D6 hydrochloride)

Debutyldronedarone D6 hydrochloride Chemical Structure

CAS No. : 1346598-70-6

规格	价格	是否有货
1 mg	￥2500	询问价格 & 货期

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生物活性	Debutyldronedarone D6 hydrochloride (SR35021 D6 hydrochloride) is deuterium labeled Debutyldronedarone. Debutyldronedarone is a major circulating active metabolite of dronedarone (HY-A0016) in humans. Debutyldronedarone exhibits a potency that is 1/10 to 1/3 of that of the parent agent^[1]^[2].
分子量	543.15
Formula	C₂₇H₃₁D₆ClN₂O₅S
CAS 号	1346598-70-6
运输条件	Room temperature in continental US; may vary elsewhere.
储存方式	Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献	[1]. Cen Xie, et al. Simultaneous determination of dronedarone and its active metabolite debutyldronedarone in human plasma by liquid chromatography-tandem mass spectrometry: application to a pharmacokinetic study.J Chromatogr B Analyt Technol Biomed Life Sci [2]. Marina Santos, et al.Synthesis and characterization of new related substances of the antiarrhythmic drug dronedarone hydrochloride. J Pharm Biomed Anal. 2015 Oct 10;114:441-6.

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