Permethrin-d5(Synonyms: 氯菊酯 d5)

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Permethrin-d5 (Synonyms: 氯菊酯 d5) 纯度: ≥98.0%

Permethrin-d5 是 Permethrin 的氘代物。Permethrin (NRDC-143) 是杀昆虫化合物，神经毒剂。

Permethrin-d5(Synonyms: 氯菊酯 d5)

Permethrin-d5 Chemical Structure

CAS No. : 1794760-19-2

规格 价格 是否有货 数量
1 mg ￥1600 In-stock
5 mg ￥3500 In-stock
10 mg ￥5800 In-stock
50 mg   询价  
100 mg   询价  

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生物活性

Permethrin-d5 (NRDC-143-d5) is the deuterium labeled Permethrin. Permethrin (NRDC-143) is an insecticide, acaricide, and insect repellent; functions as a neurotoxin, affecting neuron membranes by prolonging sodium channel activation[1][2].

体外研究
(In Vitro)

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

396.32

Formula

C21H15D5Cl2O3
CAS 号

1794760-19-2
中文名称

氯菊酯 d5
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
参考文献

  • [1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.

    [2]. Xiao X, et al. Exposure to permethrin promotes high fat diet-induced weight gain and insulin resistance in male C57BL/6J mice. Food Chem Toxicol. 2018 Jan;111:405-416.

    [3]. Smith LB, et al. CYP-mediated permethrin resistance in Aedes aegypti and evidence for trans-regulation. PLoS Negl Trop Dis. 2018 Nov 19;12(11):e0006933.

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