D-Glutamic acid-d5(Synonyms: (R)-Glutamic acid-d5)

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D-Glutamic acid-d5 (Synonyms: (R)-Glutamic acid-d5)

D-Glutamic acid-d5 ((R)-Glutamic acid-d5) 是 D-Glutamic acid 的氘代物。D-glutamic acid是L-glutamic acid的对映异构体，广泛用于药物和食品中。

D-Glutamic acid-d5(Synonyms: (R)-Glutamic acid-d5)

D-Glutamic acid-d5 Chemical Structure

CAS No. : 14341-88-9

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生物活性

D-Glutamic acid-d5 ((R)-Glutamic acid-d5) is the deuterium labeled D-Glutamic acid. D-glutamic acid, an enantiomer of L- glutamic acid, is widely used in pharmaceuticals and foods[1].

体外研究
(In Vitro)

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

152.16

Formula

C5H4D5NO4
CAS 号

14341-88-9
中文名称

D-谷氨酸 d5
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.

    [2]. Han H, et al. Changes in D-aspartic acid and D-glutamic acid levels in the tissues and physiological fluids of mice with various D-aspartate oxidase activities. J Pharm Biomed Anal. 2015 Dec 10;116:47-52.

    [3]. Chung SY, et al. IgE binding to peanut allergens is inhibited by combined D-aspartic and D-glutamic acids. Food Chem. 2015 Jan 1;166:248-53.

    [4]. Wilson W, et al. The metabolism of D- and L- glutamic acid in the rat. J Biol Chem. 1961 Feb;236:365-9.

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