L-Glutamic acid-13C5,15N(Synonyms: L-谷氨酸 13C5,15N)

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L-Glutamic acid-13C5,15N (Synonyms: L-谷氨酸 13C5,15N)

L-Glutamic acid-13C5,15N 是带有 13C 标记和 15N 标记的 L-Glutamic acid。L-Glutamic acid 作为一种兴奋性氨基酸神经递质，为谷氨酸盐受体所有亚型(代谢型红藻氨酸、NMDA 和 AMPA)的激动剂。对 DA 从多巴胺能神经末梢释放的过程有激动作用。

L-Glutamic acid-13C5,15N Chemical Structure

CAS No. : 202468-31-3

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生物活性	L-Glutamic acid-13C5,15N is the 13C- and 15N-labeled L-Glutamic acid. L-Glutamic acid acts as an excitatory transmitter and an agonist at all subtypes of glutamate receptors (metabotropic, kainate, NMDA, and AMPA). L-Glutamic acid shows a direct activating effect on the release of DA from dopaminergic terminals.
体外研究 (In Vitro)	Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs^[1]. Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.
分子量	153.09
Formula	¹³C₅H₉¹⁵NO₄
CAS 号	202468-31-3
中文名称	L-谷氨酸 13C5,15N
运输条件	Room temperature in continental US; may vary elsewhere.
储存方式	Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献	[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.

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