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Pyrimethamine-d3 (Synonyms: 乙胺嘧啶 d3)
Pyrimethamine-d3 (Pirimecidan-d3) 是 Pyrimethamine 的氘代物。Pyrimethamine(RP4753)可通过抑制二氢叶酸还原酶(DHFR)干扰四氢叶酸的合成,可作用于原生动物的感染。
Pyrimethamine-d3 Chemical Structure
CAS No. : 1189936-99-9
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1 mg | Check price and availability | ||
10 mg | Check price and availability |
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生物活性 |
Pyrimethamine-d3 (Pirimecidan-d3) is the deuterium labeled Pyrimethamine. Pyrimethamine is a medication used for protozoal infections; interferes with tetrahydrofolic acid synthesis from folic acid by inhibiting the enzyme dihydrofolate reductase (DHFR)[1][2]. |
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体外研究 (In Vitro) |
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1]. Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only. |
分子量 |
251.73 |
Formula |
C12H10D3ClN4 |
CAS 号 |
1189936-99-9 |
中文名称 |
乙胺嘧啶 d3 |
运输条件 |
Room temperature in continental US; may vary elsewhere. |
储存方式 |
Please store the product under the recommended conditions in the Certificate of Analysis. |
参考文献 |
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