Nefopam-d3(Synonyms: Fenazoxine-d3)

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上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白、同位素标记物，专注于信号通路和疾病研究领域。
Nefopam-d3 (Synonyms: Fenazoxine-d3)

Nefopam D3 (Fenazoxine D3) 是 Nefopam (Fenazoxine) 的氘代物。Nefopam 是中枢性但非阿片类化合物, 作用于体外和体内间充质细胞β-连环蛋白水平。

Nefopam-d3(Synonyms: Fenazoxine-d3)

Nefopam-d3 Chemical Structure

CAS No. : 1346747-15-6

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生物活性

Nefopam D3 (Fenazoxine D3) is a deuterium labeled Nefopam (Fenazoxine). Nefopam is a centrally-acting but non-opioid analgesic drug, and Nefopam targets β-catenin protein level in mesenchymal cells[1][2].

分子量

256.36

Formula

C17H16D3NO
CAS 号

1346747-15-6
中文名称

盐酸奈福泮 d3
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. Kim KH, et al. Rediscovery of nefopam for the treatment of neuropathic pain. Korean J Pain. 2014 Apr;27(2):103-11.

    [2]. Baht GS, et al. Pharmacologically targeting beta-catenin for NF1 associated deficiencies in fracture repair. Bone. 2017 May;98:31-36.

    [3]. Poon R, et al. A high throughput screen identifies Nefopam as targeting cell proliferation in β-catenin driven neoplastic and reactive fibroproliferative disorders. PLoS One. 2012;7(5):e37940.

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