Loperamide phenyl-d6

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Loperamide phenyl-d6 

Loperamide phenyl-d6 是 Loperamide phenyl 的氘代物。Loperamide phenyl 是洛哌酰胺 (HY-B0418A) 的一种杂质。Loperamide 是一种类阿片受体 (opioid receptor) 激动剂。

Loperamide phenyl-d6

Loperamide phenyl-d6 Chemical Structure

CAS No. : 1794737-31-7

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生物活性

Loperamide phenyl-d6 is the deuterium labeled Loperamide phenyl. Loperamide phenyl is an impurity of Loperamide (HY-B0418A). Loperamide is an opioid receptor agonist[1].

体外研究
(In Vitro)

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

559.17

Formula

C35H31D6ClN2O2
CAS 号

1794737-31-7
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.

    [2]. Hanauer, S.B., The role of loperamide in gastrointestinal disorders. Rev Gastroenterol Disord, 2008. 8(1): p. 15-20.

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