Protriptyline (N-methyl-d3) (hydrochloride)(Synonyms: 盐酸普罗替林 d3) (盐酸盐))

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Protriptyline (N-methyl-d3) (hydrochloride) (Synonyms: 盐酸普罗替林 d3) (盐酸盐))

Protriptyline (N-Methyl-d3) hydrochloride 是 Protriptyline hydrochloride 的氘代物。Protriptyline hydrochloride 是一种三环结构的抗抑郁试剂 (TCA),含有一个仲胺,可以用于抑郁和 ADHD 的相关研究。与其他抗抑郁试剂相比是独一无二的,Protriptyline是倾向于使动物精力充沛激励,并且有时用于嗜睡症的相关研究。

Protriptyline (N-methyl-d3) (hydrochloride)(Synonyms: 盐酸普罗替林 d3) (盐酸盐))

Protriptyline (N-methyl-d3) (hydrochloride) Chemical Structure

CAS No. : 1435934-21-6

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生物活性

Protriptyline (N-Methyl-d3) hydrochloride is the deuterium labeled Protriptyline hydrochloride. Protriptyline hydrochloride is a tricyclic antidepressant (TCA), specifically a secondary amine, for the treatment of depression and ADHD. Unique among the TCAs, protriptyline tends to be energizing instead of sedating, used for narcolepsy to achieve a wakefulness-promoting effect[1].

体外研究
(In Vitro)

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

266.40

Formula

C19H19D3ClN

CAS 号

1435934-21-6

中文名称

盐酸普罗替林 d3) (盐酸盐)

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • [1]. Hudgel DW. Pharmacologic treatment of obstructive sleep apnea. J Lab Clin Med. 1995;126(1):13-18.

    [2]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.

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