Tinidazole-d5(Synonyms: 替硝唑 d5)

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Tinidazole-d5 (Synonyms: 替硝唑 d5)

Tinidazole-d5 是 Tinidazole 的氘代物。Tinidazole，具有口服活性的抗菌剂，是一种对厌氧菌和原生动物具有选择性抗菌活性的 5-硝基咪唑。

Tinidazole-d5 Chemical Structure

CAS No. : 1216767-04-2

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生物活性	Tinidazole-d5 is the deuterium labeled Tinidazole. Tinidazole, an orally available antibacterial agent, is a 5-nitroimidazole with selective activity against anaerobic bacteria and protozoa^[1].
体外研究 (In Vitro)	Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs^[1]. Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.
分子量	252.30
Formula	C₈H₈D₅N₃O₄S
CAS 号	1216767-04-2
中文名称	替硝唑 d5
运输条件	Room temperature in continental US; may vary elsewhere.
储存方式	Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献	[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [2]. Nord CE, et al. Tinidazole–microbiology, pharmacology and efficacy in anaerobic infections. Infection. 1983;11(1):54-60.

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