Vitamin D2-d6(Synonyms: Ergocalciferol-d6; Calciferol-d6; Ercalciol-d6)

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Vitamin D2-d6 (Synonyms: Ergocalciferol-d6; Calciferol-d6; Ercalciol-d6)

Vitamin D2-d6 (Ergocalciferol-d6) 是 Vitamin D2 的氘代物。Vitamin D2 (Ergocalciferol),来自食物或膳食补充剂,可用作维生素 D 的补充剂。

Vitamin D2-d6(Synonyms: Ergocalciferol-d6;  Calciferol-d6;  Ercalciol-d6)

Vitamin D2-d6 Chemical Structure

CAS No. : 1311259-89-8

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生物活性

Vitamin D2-d6 (Ergocalciferol-d6) is the deuterium labeled Vitamin D2. Vitamin D2 (Ergocalciferol), drived from plant sources or dietary supplements, could be used as supplement of Vitamin D[1][2].

体外研究
(In Vitro)

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

402.69

Formula

C28H38D6O

CAS 号

1311259-89-8

中文名称

维生素 D2 d6

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • [1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.

    [2]. Sagar U Nigwekar, et al. Ergocalciferol and cholecalciferol in CKD. Am J Kidney Dis. 2012 Jul;60(1):139-56.

    [3]. R Gagnemo-Persson, et al. Chicken parathyroid hormone gene expression in response to gastrin, omeprazole, ergocalciferol, and restricted food intake. Calcif Tissue Int. 1997 Sep;61(3):210-5.

    [4]. F Ariyuki, et al. Growth retardation induced in rat fetuses by maternal fasting and massive doses of ergocalciferol. J Nutr. 1987 Feb;117(2):342-8.

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