Artemether-d3(Synonyms: Dihydroqinghaosu methyl ether-d3; Dihydroartemisinin methyl ether-d3; SM224-d3)

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白、同位素标记物,专注于信号通路和疾病研究领域。
Artemether-d3 (Synonyms: Dihydroqinghaosu methyl ether-d3; Dihydroartemisinin methyl ether-d3; SM224-d3)

Artemether-d3 (Dihydroqinghaosu methyl ether-d3) 是 Artemether 的氘代物。Artemether是抗疟疾化合物,可作用于恶性疟疾的耐药株。

Artemether-d3(Synonyms: Dihydroqinghaosu methyl ether-d3;  Dihydroartemisinin methyl ether-d3;  SM224-d3)

Artemether-d3 Chemical Structure

CAS No. : 93787-85-0

规格 是否有货
2.5 mg Check price and availability
10 mg Check price and availability
25 mg Check price and availability
50 mg Check price and availability
100 mg Check price and availability

* Please select Quantity before adding items.

生物活性

Artemether-d3 (Dihydroqinghaosu methyl ether-d3) is the deuterium labeled Artemether. Artemether is an antimalarial for the treatment of resistant strains of falciparum malaria.

体外研究
(In Vitro)

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

301.39

Formula

C16H23D3O5

CAS 号

93787-85-0

中文名称

蒿甲醚 d3

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • [1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.

    [2]. Xiao, S., et al., Recent investigations of artemether, a novel agent for the prevention of schistosomiasis japonica, mansoni and haematobia. Acta Trop, 2002. 82(2): p. 175-81.

    [3]. Wu, Z.P., et al., Inhibitive effect of artemether on tumor growth and angiogenesis in the rat C6 orthotopic brain gliomas model. Integr Cancer Ther, 2009. 8(1): p. 88-92.

所有产品仅用作科学研究或药证申报,我们不为任何个人用途提供产品和服务