Benzamide-15N(Synonyms: NSC-3114-15N; Benzenecarboxamide-15N; Phenylamide-15N)

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Benzamide-15N (Synonyms: NSC-3114-15N; Benzenecarboxamide-15N; Phenylamide-15N) 纯度: ≥98.0%

Benzamide-15N (NSC-3114-15N) 是一种 15N 标记的 Benzamide. Benzamide 可抑制 poly(ADP-ribose) polymerase (PARP).

Benzamide-15N(Synonyms: NSC-3114-15N;  Benzenecarboxamide-15N;  Phenylamide-15N)

Benzamide-15N Chemical Structure

CAS No. : 31656-62-9

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生物活性

Benzamide-15N (NSC-3114-15N) is a 15N-labeled Benzamide. Benzamide inhibits poly(ADP-ribose) polymerase (PARP)[1][2].

体外研究
(In Vitro)

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

122.13

Formula

C7H715NO

CAS 号

31656-62-9

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
参考文献
  • [1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.

    [2]. Cosi C, et al. Benzamide, an inhibitor of poly(ADP-ribose) polymerase, attenuates methamphetamine-induced dopamine neurotoxicity in the C57B1/6N mouse. Brain Res. 1996;735(2):343-348.

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