Brodimoprim-d6(Synonyms: Ro 10-5970-d6)

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Brodimoprim-d6 (Synonyms: Ro 10-5970-d6)

Brodimoprim-d6 (Ro 10-5970-d6) 是一种氘代的Brodimoprim。Brodimoprim, 是一种甲氧苄啶类似物,是一种口服活性二氢叶酸还原酶 (dihydrofolate reductase) 抑制剂。Brodimoprim 对广谱革兰氏阴性和革兰氏阳性细菌具有高度活性。

Brodimoprim-d6(Synonyms: Ro 10-5970-d6)

Brodimoprim-d6 Chemical Structure

CAS No. : 1346599-93-6

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生物活性

Brodimoprim-d6 (Ro 10-5970-d6) is a deuterium labeled Brodimoprim. Brodimoprim, a trimethoprim analogue, is an orally active dihydrofolate reductase inhibitor. Brodimoprim is highly active against a broad spectrum of gram-negative and gram-positive bacteria[1].

分子量

345.22

Formula

C13H9D6BrN4O2

CAS 号

1346599-93-6

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • [1]. Weidekamm E. Pharmacokinetics of brodimoprim. J Chemother. 1993;5(6):475-479.

    [2]. Marchese A, et al. Brodimoprim: effects of subminimal inhibitory concentrations on virulence traits of respiratory and urinary tract pathogens, and on plasmid transfer and stability. J Chemother. 1996;8(3):171-177.

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