Rifapentine-d9(Synonyms: DL 473-d9; Cyclopentylrifampicin-d9)

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白、同位素标记物，专注于信号通路和疾病研究领域。
Rifapentine-d9 (Synonyms: DL 473-d9; Cyclopentylrifampicin-d9)

Rifapentine-d9 (DL 473-d9) 是 Rifapentine 的氘代物。Rifapentine (DL 473)是抗生素，可用于肺结核。

Rifapentine-d9 Chemical Structure

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生物活性	Rifapentine-d9 (DL 473-d9) is the deuterium labeled Rifapentine. Rifapentine (DL 473) is an antibiotic compound used in the treatment of tuberculosis.
体外研究 (In Vitro)	Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs^[1]. Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.
分子量	886.09
Formula	C₄₇H₅₅D₉N₄O₁₂
中文名称	利福喷丁 d9
运输条件	Room temperature in continental US; may vary elsewhere.
储存方式	Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献	[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [2]. Sharma, S.K., et al., Rifamycins (rifampicin, rifabutin and rifapentine) compared to isoniazid for preventing tuberculosis in HIV-negative people at risk of active TB. Cochrane Database Syst Rev, 2013. 7: p. CD007545.

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