7-Dehydrocholesterol-d7(Synonyms: 7-去氢胆固醇 d7)

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7-Dehydrocholesterol-d7 (Synonyms: 7-去氢胆固醇 d7)

7-Dehydrocholesterol-d7 是 7-Dehydrocholesterol 的氘代物。7-Dehydrocholesterol 是胆固醇和维生素 D3 的生物合成前体。

7-Dehydrocholesterol-d7(Synonyms: 7-去氢胆固醇 d7)

7-Dehydrocholesterol-d7 Chemical Structure

CAS No. : 388622-58-0

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生物活性

7-Dehydrocholesterol-d7 is the deuterium labeled 7-Dehydrocholesterol. 7-Dehydrocholesterol is biosynthetic precursor of cholesterol and vitamin D3[1][2].

体外研究
(In Vitro)

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

391.68

Formula

C27H37D7O
CAS 号

388622-58-0
中文名称

7-去氢胆固醇 d7
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.

    [2]. Xu L, et al. Oxysterols from free radical chain oxidation of 7-dehydrocholesterol: product and mechanistic studies. J Am Chem Soc. 2010 Feb 24;132(7):2222-32.

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