Methyl mycophenolate-d6

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Methyl mycophenolate-d6 

Methyl mycophenolate-d6 是 Methyl mycophenolate 的氘代物。Methyl mycophenolate 是霉酚酸的甲酯，也存在于海洋真菌 Phaeosphaeria spartinae 中。

Methyl mycophenolate-d6

Methyl mycophenolate-d6 Chemical Structure

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生物活性

Methyl mycophenolate-d6 is the deuterium labeled Methyl mycophenolate. Methyl mycophenolate is a methyl ester of mycophenolic acid and is also found in marine-derived fungus Phaeosphaeria spartinae[1][2].

体外研究
(In Vitro)

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

340.40

Formula

C18H16D6O6
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.

    [2]. Elsebai MF. Secondary metabolites from the marine-derived fungus Phaeosphaeria spartinae. Nat Prod Res. 2019 Aug 23:1-6.

    [3]. Gainer FE, et al. Thin-layer chromatography of mycophenolic acid and related compounds. J Chromatogr. 1971 Feb 3;54(3):446-8.

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