Pirimiphos-methyl-d6

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Pirimiphos-methyl-d6 

Pirimiphos-methyl-d6 是 Pirimiphos-methyl 的氘代物。Pirimiphos-methyl 是一种快速作用的有机磷杀虫剂和杀螨剂，可抑制目标生物体中的乙酰胆碱酯酶 (AChE)。Pirimiphos-methyl 经常在农业谷物的储存过程中用于预防和控制甲虫，鼻子甲虫，飞蛾和埃氏小球藻。

Pirimiphos-methyl-d6

Pirimiphos-methyl-d6 Chemical Structure

CAS No. : 1793055-06-7

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生物活性

Pirimiphos-methyl-d6 is the deuterium labeled Pirimiphos-methyl. Pirimiphos-methyl is a rapid-acting organophosphorus insecticide and acaricide, causing inhibition of AChE in target organisms. Pirimiphos-methyl is often used for prevention and control of beetles, snout beetles, moths and Ephestia cautella during storage of agricultural grains[1][2][3].

体外研究
(In Vitro)

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

311.37

Formula

C11H14D6N3O3PS
CAS 号

1793055-06-7
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.

    [2]. Shizhuang Weng, et al. Detection of Pirimiphos-Methyl in Wheat Using Surface-Enhanced Raman Spectroscopy and Chemometric Methods. Molecules. 2019 Apr 30;24(9):1691.

    [3]. Pål A Olsvik, et al. In Vitro Toxicity of Pirimiphos-Methyl in Atlantic Salmon Hepatocytes. Toxicol In Vitro. 2017 Mar;39:1-14.

    [4]. Esther Borrás, et al. Atmospheric Degradation of the Organothiophosphate Insecticide – Pirimiphos-methyl. Sci Total Environ. 2017 Feb 1;579:1-9.

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