Cetirizine D4 dihydrochloride(Synonyms: 盐酸西替利嗪 D4)

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Cetirizine D4 dihydrochloride (Synonyms: 盐酸西替利嗪 D4)

Cetirizine D4 dihydrochloride 是Cetirizine 的氘代物。Cetirizine 是羟嗪的羧化代谢物，是第二代抗组胺药。Cetirizine是一种特异的、口服有效的、H1 受体 的长效拮抗剂。Cetirizine 标记抗过敏特性，抑制过敏反应期间嗜酸性粒细胞趋化。

Cetirizine D4 dihydrochloride Chemical Structure

规格		是否有货
100 mg		询价
250 mg		询价
500 mg		询价

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生物活性	Cetirizine D4 dihydrochloride is a deuterium labeled Cetirizine. Cetirizine, a second-generation antihistamine and the carboxylated metabolite of hydroxyzine, is a specific, orally active and long-acting histamine H1-receptor antagonist. Cetirizine marks antiallergic properties and inhibits eosinophil chemotaxis during the allergic response^[1]^[2]^[3].
分子量	465.83
Formula	C₂₁H₂₃D₄Cl₃N₂O₃
中文名称	盐酸西替利嗪 D4
运输条件	Room temperature in continental US; may vary elsewhere.
储存方式	Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献	[1]. Caroline M. Spencer, et al. Cetirizine. Drugs 46 (6): 1055•1080, 1993. [2]. Shih MY, et al. Influence of cetirizine and levocetirizine on two cytokines secretion in human airway epithelial cells. Allergy Asthma Proc. 2008 Sep-Oct;29(5):480-5. [3]. Shimizu T, et al. Cetirizine, an H1-receptor antagonist, suppresses the expression of macrophage migration inhibitory factor: its potential anti-inflammatory action. Clin Exp Allergy. 2004 Jan;34(1):103-9.

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