Flumethasone-d3(Synonyms: Flumetasone-d3)

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白、同位素标记物，专注于信号通路和疾病研究领域。
Flumethasone-d3 (Synonyms: Flumetasone-d3)

Flumethasone-d3 (Flumetasone-d3) 是 Flumethasone 的氘代物。Flumethasone 是一种皮质类固醇，是一种局部用药，与 Clioquinol 联用于外耳炎和耳真菌病的研究, Flumethasone 作用于动物模型时, 抗炎活性比 Cortisone 高 420 倍。

Flumethasone-d3 Chemical Structure

CAS No. : 2280940-16-9

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生物活性	Flumethasone-d3 (Flumetasone-d3) is the deuterium labeled Flumethasone. Flumethasone is a corticosteroid for topical use, in combination with Clioquinol for the treatment of otitis externa and otomycosis. Flumethasone shows fully 420 times the potency of cortisone in an animal model for anti-inflammatory activity.
体外研究 (In Vitro)	Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs^[1]. Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.
分子量	413.47
Formula	C₂₂H₂₅D₃F₂O₅
CAS 号	2280940-16-9
中文名称	氟米松 d3
运输条件	Room temperature in continental US; may vary elsewhere.
储存方式	Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献	[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.

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